摘要
聚集诱导发光分子在有机光电功能材料领域有着重要的应用价值.利用常见的ACQ−活性萘酰亚胺染料,通过典型的铃木偶联反应,在萘酰亚胺荧光团的4位引入一个去平面化苯环,设计并合成两个新的聚集诱导发光(Aggregation-Induced Emission,AIE)分子NIRF2和NIRF6.通过^(1)H、^(13)C NMR和HRMS谱对其进行结构表征.通过紫外−可见光谱、荧光发射光谱和动态激光散射测试研究二者结构与聚集诱导发光的构效关系.最后,NIRF2和NIRF6成功应用于Hela细胞的细胞质成像.研究表明,提出的优化设计策略可以实现萘酰亚胺基AIE活性分子的构建.
Aggregation-induced emission(AIE)-active materials show important applications in organic photoelectric functional materials.By introducing a phenyl ring,a deplanarization core into the 4-site of naphthalimide chromophore through the typical Suzuki coupling reaction,two new AIE molecules(NIRF2 and NIRF6)based on the common ACQ-active naphthalimide dye were designed and synthesized.Their structures were fine characterized by^(1)H&^(13)C NMR and HRMS spectra.The structure-properties relationships were discussed by UV-vis and fluorescent spectra and dynamic laser scattering tests.Finally,both NIRF2 and NIRF6 were successfully applied to image the cytoplasm of the Hela cells.The study results show that the optimized designing strategy can achive the naphthalimide-based AIE-active molecules.
作者
黄文灵
蒋娜
朱颖
黄婉玲
瞿祎
HUANG Wenling;JIANG Na;ZHU Ying;HUANG Wanling;QU Yi(School of Chemistry and Chemical Engineering,Shanghai University of Engineering Science,Shanghai 201620,China)
出处
《上海工程技术大学学报》
CAS
2022年第3期301-308,共8页
Journal of Shanghai University of Engineering Science
关键词
萘酰亚胺
聚集诱导发光
细胞成像
naphthalimide
aggregation-induced emission(AIE)
cell imaging
作者简介
黄文灵(2000-),女,在读硕士,研究方向为有机光电功能材料.E-mail:1216926181@qq.com;通信作者:瞿祎(1984-),男,副教授,博士,研究方向为有机光电功能材料.E-mail:yiqu@sues.edu.cn
