摘要
新冠状病毒病(COVID-19)自2019年12月在我国发现以来,目前已在全球213个国家爆发,540多万人受累,并导致近35万人死亡,WHO将其定义为全球大流行。COVID-19除了表现为呼吸系统病变,在重症患者还可能合并有其他脏器损伤,部分患者可出现肾脏损伤,如发生血尿、蛋白尿,血尿素氮或血清肌酐水平升高等;危重症患者中急性肾损伤的发生率较高且影响患者预后。本文将从COVID-19患者肾损伤流行病学及临床特点、发病机制、病理表现、治疗和预后等方面综述,希望能从肾脏病专科角度为COVID-19的防控提供相关信息。
Since its discovery in China in December 2019, the new coronavirus disease(COVID-19) has now broken out in 213 countries around the world, affecting more than 5.4 million people and causing the death of nearly 350,000 people.WHO has defined it as a global pandemic.In addition to respiratory system involvement, COVID-19 was also accompanied by other organs injuries, especially in severely ill patients, some of whom showed kidney damage manifesting as hematuria, proteinuria, and increased levels of blood urea nitrogen or serum creatinine.The incidence of acute kidney injury in critically ill patients was high and it affected their prognosis.This article reviewed the epidemiology, clinical features,pathogenesis, pathological manifestations, treatment, and prognosis of kidney injury in COVID-19 patients,hoping to provide relevant information for the prevention and control of COVID-19 from the perspective of nephrology.
作者
杨光
刘洋
赵佳慧
程庆砾
Yang Guang;Liu Yang;Zhao Jiahui;Cheng Qingli(Department of Nephrology,Second Medical Center of Chinese PLA General Hospital,National Clinical Research Center for Geriatric Diseases,Beijing 100853,China)
出处
《中华肾病研究电子杂志》
2020年第3期127-130,共4页
Chinese Journal of Kidney Disease Investigation（Electronic Edition）
基金
国家老年疾病临床医学研究中心开放课题(NCRCCPLAGH-2018012)
解放军总医院第二医学中心保健课题(NLBJ-2019006)
作者简介
通信作者:程庆砾,Email:qlcheng64@163.com
