摘要
本文对100名健康人(对照组),108例糖尿病不伴有视网膜病变的患者(非糖网组),108例糖尿病伴有视网膜病变的患者(糖网组)进行眼球结膜和甲皱微循环的观察。结果表明:糖尿病患者眼球结膜和手指甲皱微循环,在微血管、微血流及微血管通透性三方面均有明显的障碍。但眼球结膜微循环的微血管和微血流的异常发生率高于手指甲皱。伴有视网膜病变的糖尿病患者微血流流态及微血管通透性的异常发生率明显地高于不伴有视网膜病变的糖尿病患者,但两者微血管形态的异常没有明显的差别。视网膜病变严重的糖尿病患者眼球结膜微血流流态的障碍更为严重。上述结果提示:糖尿病患者有明显的微循环障碍,而这是发生视网膜病变的病理生理学基础。
The microcirculation of the bulbar conjunctiva and finger nail fold was observed among 108 cases of diabetes mellitus without fundoscopic retinopathy(group 1),108 cases with fundoscopic retinopathy(group 2)and 100 cases of non-diabetics as control(group 3).It was found that there were more marked disturbances in microvessels,blood flow and microvascular permeability of the bulbar conjunctiva and nail fold in groups 1 and 2 than in group 3.Moreover,there were higher incidences of disturbances of the microvessels and blood flow in the bulbar conjunctiva than in the nail fold.No significant difference in the walls of microvessels was found between groups 1 and 2 but the distubances of blood flow and microvascular permeability in group 2 were more severe than those in group 1.Significant abnormality of blood flow in the bulbar conjunctiva was found in the diabetics with proliferative retinopathy.The results suggest that the disturbances of microcirculation in diabetics might be the pathological basis in the development of diabetic retinopathy.
出处
《上海医学》
CAS
1983年第11期646-649,共4页
Shanghai Medical Journal
