摘要
1979~1985年住院新生儿患者中血pH≤7.0有103例,占同期住院新生儿1.9%。导致重度酸中毒的原发疾病有20种,以呼吸系统疾病占首位(51.5%),败血症第二位(17.5%),消化系疾病第三位(13.6%)。治愈好转率仅24.3%,呼吸系统疾病,败血症,缺血缺氧性脑病,颅内出血,先天性青紫型心脏病预后差。而消化系统疾病预后较好,早产儿晚期酸中毒预后好。生后一周内发病率与病死率均高,血PCO_(2)升高时预后亦差。对新生儿重度酸中毒的防治问题进行了讨论。
Severe neonatal acidosis(pH 7 or less)occurred in 103 cases(1.9%)among 6,509 cases admitted from 1978 to 1985.Of these cases,50 were term babies,48 preterm,3 post-term and 2 small-for-date.There were 20 primary diseases causing severe neonatal acidosis,They were respiratory tract diseases,including meconium aspiration,pneumonia.respiratory distress syndrome and pulmonary dysplasia(53 cases,51.5%);septicemia(18 cases,17.5%);gastrointestinal disorders,including diarrhea,necrotizing enterocolitis,perforation of stomach and intestinal obstruction(14 cases.13.5%)and others as hypoxic ischemic encephalopathy and/or intracranial hemorrhage,congenital cynotic heart disease,sclerema neonatorium and late acidosis in pretcrm babies(18 cases,17.5%).The major symptoms were respiratory distress(90.3%),apnca(48.5%),cynosis(86.4%),grey face(78.6%)and hypothermia(77.7%).The mortality was high(73.8%),especially in those babies with respiratory tract diseases(84.9%)or in babies less than 7 days of age(87.5%).16 of the lethal cases were complicated with massive pulmonary hemorrhage.The prognosis was grave for both term and preterm babies.
出处
《上海医学》
CAS
1988年第3期149-152,共4页
Shanghai Medical Journal
