摘要
我们用酶免疫法检测了68例各型病毒性肝炎患者的IgE-抗HBc和总IgE。慢性乙肝中IgE-抗HBc的检出率和水平均显著高于急性乙肝。急性乙肝IgE-抗HBc的出现为一过性,持续阳性提示有慢性化趋势。HBsAg阴性的甲肝患者,IgE-抗HBc检测均为阴性。在HBsAg阳性肝炎中,51.7%的患者同时有IgE-抗HBc阳性和总IgE的增高。IgE-抗HBc是总抗HBc的一部分。IgE-抗HBc的检出说明HBV感染可诱生特异性的IgE,可能是总IgE增高的原因之一。
Serum IgE and IgE anti-HBc were determined by ELISA in 68 cases with viral hepatitis.We found that the positive percentage and value of P/N of IgE anti-HBc were significantly higher in chronic hepatitis B than in acute stage.However,the existence of IgE anti-HBc was transient in acute cases.If IgE anti-HBc was persistently positive,the patient might have a tendency of chronicity.IgE anti-HBc and increased titer of total IgE were found in 51.7%of hepatitis patients with positive HBsAg.IgE anti-HBc is one part of total anti-HBc.The existence of IgE anti-HBc indicates that the specific IgE is induced by HBV infection,it might be one of the reasons for the elevation of total IgE in hepatitis B.
出处
《上海医学》
CAS
1988年第9期519-521,共3页
Shanghai Medical Journal
