摘要
结直肠癌患者死亡的主要原因是侵袭转移,因此控制其转移对延长晚期结直肠癌患者的生存期具有重要意义。从病因病机出发,结合古典医籍、各家学说、临床与基础实验文献,提出结直肠癌转移的中医理论构想:正气亏虚(尤其是脾虚)是内在根本,癌毒内结(痰、瘀、毒、潜伏下来的致病因子)是必要条件,经络传注是主要途径,诱因则可成为导火索,最终造成癌毒在经络之间、脏腑之间、经络脏腑之间的传变。认为防治结直肠癌侵袭转移当以健脾为主,结合各种祛邪手段(化痰、软坚、解毒、化瘀等),修复受损之络脉。
The main cause of death in colorectal cancer is invasion and metastasis.It is important to control the metastasis for prolonging the survival period of patients with advanced colorectal cancer.Based on the etiology and pathogenesis,combined with classical medical records,various medical theories,clinical and basic experimental literature,this paper puts forward the TCM concept of recurrence and metastasis of colorectal cancer.Deficiency of healthy qi(especially spleen deficiency)is its internal root cause,cancer toxin(phlegm,blood stasis,toxin,latent pathogenic factor)is its necessary condition,meridian transmission and injection is its main way,and inducement can be the fuse.Finally,it causes the transmission of cancer toxin between meridians and collaterals,Zang organs and Fu organs,and meridians and Zang-Fu organs.It is proposed that the prevention and treatment of colorectal cancer invasion and metastasis should be based on strengthening the spleen,combining with various means of eliminating pathogenic factors(reducing phlegm,softening hardness,detoxifying,removing stasis,etc.)to repair the damaged collaterals.
作者
林怡
陶丽
LIN Yi;TAO Li(Department of Oncology,Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)
出处
《上海中医药杂志》
2020年第2期6-9,共4页
Shanghai Journal of Traditional Chinese Medicine
基金
国家自然科学基金青年基金项目(81603548)
国家卫计委医药卫生科技发展研究中心“重大新药创制”科技重大专项(2017ZX09304001).
关键词
结直肠癌
转移
病因病机
正气亏虚
癌毒内结
经络传注
中医药疗法
colorectal cancer
metastasis
etiology and pathogenesis
deficiency of healthy qi
internal accumulation of cancer toxin
meridian transmission and injection
TCM therapy
作者简介
林怡,女,硕士研究生,主要从事中西医结合防治消化系统恶性肿瘤的临床和基础研究工作;通讯作者:陶丽,副主任医师,硕士研究生导师。E-mail:taoli20121228@163.com
