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山药的研究进展及其抗衰老的网络药理学分析 被引量:40

Research Progress of Chinese Yam and its Network Pharmacological Analysis of Anti-Aging
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摘要 山药是一种多年生缠绕草本植物,广泛分布于我国中部、东部、东北部,韩国、日本也有分布。山药主要含有淀粉、氨基酸、多糖、微量元素、脂肪酸、皂苷、多酚等化学成分,具用抗氧化、抗炎、抗肿瘤、抗癌、调节血糖血脂、调节肠道菌群等药理作用,其复方还被广泛的应用于临床实践,治疗诸多的老年性疾病。本研究在综述近年来山药研究进展的同时,还应用了网络药理学方法对山药抗衰老的机制进行了分析,为山药进一步的研究和开发提供参考。 Chinese yam is a perennial twining herb,mainly distributed in the middle,eastern and northeastern of China.Chinese yam mainly contains starch,amino acids,polysaccharides,trace elements,fatty acids,saponins,polyphenols and other chemical compositions.Chinese yam has many different pharmacological effects such as anti-oxidation,antiinflammatory,anti-tumor,anti-cancer,and regulation of blood sugar,blood lipid,intestinal flora.Compound prescription for Chinese yam is widely used in clinical practice to treat many senile diseases.This research not only has summarized the research progress of Chinese yam,but also has applied the network pharmacology method to analyze the anti-aging mechanism of Chinese yam.This research aims to provide a reference for further research on Chinese yam and development of it.
作者 胡聪 孟祥龙 宁晨旭 苏晓娟 张朔生 Hu Cong;Meng Xianglong;Ning Chenxu;Su Xiaojuan;Zhang Shuosheng(College of Chinese Materia Medica and food engineering,Shanxi University of Chinese medicine,Jinzhong,030619,China;School of Pharmacy,Jiangxi Science and Technology Normal University,Nanchang,330013,China)
出处 《世界科学技术-中医药现代化》 CSCD 北大核心 2020年第7期2348-2365,共18页 Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金 山西省科学技术厅重点研发计划重点项目(201603D3112002):12种优质中药饮片规范化炮制加工工艺及质量标准研究,负责人:张朔生,立项单位:山西省科技厅
关键词 山药 成分 药理作用 临床应用 抗衰老 网络药理学 Chinese yam Composition Pharmacological effect Clinical application Anti-aging Network pharmacology
作者简介 通讯作者:张朔生,教授,硕士,主要研究方向:中药炮制与药效物质基础研究。
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