摘要
目的急性心肌梗死合并心律失常是临床常见病症,严重影响患者生活质量,本研究探讨门冬氨酸钾镁联合酒石酸美托洛尔注射液与盐酸胺碘酮治疗疗效,为提高患者生活质量提供参考。方法将2017-01-01—2019-01-01上蔡县人民医院收治的108例急性心肌梗死合并心律失常患者依据治疗方法分为每组54例。对照组采用酒石酸美托洛尔注射液治疗,观察组采用门冬氨酸钾镁联合酒石酸美托洛尔注射液与盐酸胺碘酮治疗。观察两组患者临床疗效、左室射血分数、平均住院时间和并发症发生情况。结果观察组总有效率为94.44%,高于对照组的77.78%,χ~2=6.271,P=0.012;观察组左室射血分数为(63.79±5.88)%,高于对照组的(60.12±4.69)%,t=4.587,P=0.041;平均住院时间为(9.67±1.22)d,低于对照组的(12.28±1.46)d,t=15.721,P<0.001。观察组并发症发生率为1.85%,低于对照组的14.81%,差异有统计学意义,χ~2=5.939,P=0.015。结论门冬氨酸钾镁联合酒石酸美托洛尔注射液与盐酸胺碘酮治疗急性心肌梗死合并心律失常疗效较好,可改善患者左室射血分数,缩短住院时间,减少并发症的发生。
OBJECTIVE Acute myocardial infarction combined with arrhythmia is a common clinical disease,which seriously affects the quality of life of patients.This study aims to investigate the efficacy of potassium and magnesium aspartate combined with metoprolol tartrate injection and amiodarone hydrochloride in order to improve the quality of life of patients.METHODS A total of 108 patients with acute myocardial infarction and arrhythmia admitted to Shangcai County People’s Hospital from January 01,2017 to January 01,2019 were divided into 54 groups according to the treatment method.The control group was treated with betaloc,while the observation group was treated with potassium and magnesium asparate combined with betaloc and amiodarone hydrochloride.Clinical efficacy,left ventricular ejection fraction,average length of stay and complications were observed in the two groups.RESULTS The total effective rate of the observation group was 94.44%,which was higher than that of the control group(77.78%),χ~2=6.271,P=0.012.The left ventricular ejection fraction of the observation group was(63.79±5.88)%,which was higher than that of the control group(60.12±4.69)%,t=4.587,P=0.041.Mean hospital stay was(9.67±1.22)d,which was lower than that of the control group(12.28±1.46)d,t=15.721,P<0.001.The incidence of complications in the observation group was 1.85%,lower than that in the control group(14.81%),and the difference was statistically significant,χ~2=5.939,P=0.015.CONCLUSION Potassium and magnesium aspartate combined with betaloc and amiodarone hydrochloride is effective in the treatment of acute myocardial infarction with arrhythmia,which can improve left ventricular ejection fraction,shorten hospital stay and reduce complications.
作者
王尚华
关亚东
WANG Shang-hua;GUAN Ya-dong(Department of Cardiology,Shangcai County People's Hospital,Shangcai 463800,P.R.China)
出处
《社区医学杂志》
2019年第23期1522-1524,1528,共4页
Journal Of Community Medicine
关键词
门冬氨酸钾镁
酒石酸美托洛尔注射液
盐酸胺碘酮
急性心肌梗死
心律失常
potassium aspartate magnesium
metoprolol tartrate injection
amiodarone hydrochloride
acute myocardial infarction
arrhythmology
作者简介
通讯作者:王尚华,女,河南驻马店人,主治医师,主要从事心内科疾病诊治的临床研究工作。Tel:86-396-6908797 E-mail:fuqingyelh@163.com
