摘要
PM2.5 are fine inhalable particles with diameters that are generally 2.5 micrometers and smaller and are characterized by a small particle size,a large surface area,and a strong toxin absorption ability[1-3].PM2.5 contains heavy metals and organic pollutants that are harmful to human health and exert carcinogenic,teratogenic,and mutagenic effects[4-7].PM2.5 has been classified as a human carcinogen by the International Agency for Research on Cancer(IARC)[2].The economy has developed rapidly making air pollution a serious environmental health problem in China.The purpose of this study was to explore the differentially expressed genes and pathways after a PM2.5 exposure in the human bronchial epithelial(HBE)cells via gene chip technology and bioinformatics analysis.
基金
supported by the basic research programs of Shenzhen Science and Technology Innovation Committee to XU Xin Yun [JCYJ20170413101713324].
作者简介
WANG Bing Yu and CAI Ying contributed equally to this work;Correspondence should be addressed to XU Xin Yun,Tel:86-755-25609527,E-mail:xyxu2008@163.com;Biographical notes of the first authors:WANG Bing Yu,female,born in 1993,MPH,majoring in molecular toxicology;Biographical notes of the first authors:CAI Ying,female,born in 1995,MPH,majoring in environmental toxicology.
