摘要
葡萄糖五乙酸酯是一种重要的糖类有机化合物,在饮料食品、化工和生物医药等许多领域应用比较广泛。本文主要研究了以葡萄糖和乙酸酐为主要原料,在无水氯化锌的催化作用下进行合成葡萄糖五乙酸酯的方法,并深入探讨了诸因素对反应收率的影响。结果表明,葡萄糖五乙酸酯合成的最佳条件为:葡萄糖的用量为2.50 g,酯化合成所需葡萄糖和乙酸酐的物质的量之比为1∶7,酯化所需要的催化剂的量为0.70 g,反应时间一般为3 h,反应温度控制在95℃。在上述条件下,酯化的产率能达到62.70%。
Glucose pentaacetate is a kind of important organic compounds,and is widely used in drink,food,chemical and biological medicine and other fields.In this paper,using glucose and acetic anhydride as main raw materials,anhydrous zinc chloride as the catalyst,glucose pentaacetate was synthesized,and the factors influencing on the yield of reaction were investigated.The results showed that optimum conditions for synthesis of glucose pentaacetate were determined as follows:the amount of glucose 2.50 g,the ratio of glucose to acetic anhydride 1∶7,the catalyst amount 0.70 g,the reaction time 3 h,the reaction temperature 95℃.Under above conditions,the yield of the reaction was 62.70%.
作者
何媛媛
霍成玉
马龙
方宏树
HE Yuan-yuan;HUO Cheng-yu;MA Long;FANG Hong-shu(Qinghai Application and Test Center of Geology and Mineral Resources,Xining 810008,China)
出处
《当代化工》
CAS
2020年第10期2112-2115,共4页
Contemporary Chemical Industry
基金
青海省重点研发与转化项目(项目编号:2019-SP-129)
关键词
葡萄糖五乙酸酯
葡萄糖
乙酸酐
酯化
氯化锌
Glucose pentoacetate
Glucose
Acetic anhydride
Esterification
Zinc chloride
作者简介
何媛媛(1989-),女,青海省西宁市人,助理工程师,2013年毕业于延安大学化学工程与工艺(工业分析方向)专业,研究方向:实验测试技术。E-mail:1173368846@qq.com。
