摘要
传统中药方剂锡类散治疗十二指肠球部溃疡有较好疗效,过去已有报导。但由于缺乏严格双盲对比,不易评价其确切疗效。
Good therapeutic effect of Shileisan (a chinese medicine) in the treatment of duodenal ulcer has been reported by many authors. However it needs scientific prove. By using double blind experiment we analyzed 56 cases of duodenal ulcer (in bulb and pyloric canal) in active stages (stage A1 and A2) confirmed by fiber gastroscopy. They were divided randomly in to two groups-one receiving Shleisan, the other a placebo-compared double blindly, and reexamed three weeks later. The results were as follows: The healing rates of ulcer (ulcer in stage S) were 64.7% in the therapeutic group and 31.8% in the control group (P<0.05). the effective rates (ulcer in stages S and H) were 85.29% in the therapeutic group and 59.09% in the control group (P<0.05). These results indicate that Shileisan possesses really a good effect in the treatment of duodenal ulcer. Our study also shows that both hydrochloric acid (BAO and MAO) secretion and serum gastrin level varied only slightly before and after the treatment. This explains that Shileisan has focal effect only without influence on gastric acid and serum gastrin. In view of the absence of side-effects such as inhibition of bone marrow and liver damage during the treatment, we think that Shiteisan is quite a safe and effective drug.
出处
《天津医药》
CAS
1984年第1期36-38,共3页
Tianjin Medical Journal
