摘要
目的探究连续性血液净化对弥漫性腹膜炎并发感染性休克患者炎性反应及急性生理学与慢性健康状况评分Ⅱ(APACHE-Ⅱ评分)的影响。方法回顾性分析2017年3月-2019年12月我院诊治的弥漫性腹膜炎并发感染性休克患者85例临床资料,根据治疗方法不同分组,其中采用基础治疗的42例患者临床资料归为对照组,将接受基础治疗和连续性血液净化治疗的43例患者临床资料归为观察组,比较两组炎性反应及APACHE-Ⅱ评分。结果治疗后,观察组血清降钙素原(PCT)、C-反应蛋白(CRP)、白介素因子-8(IL-8)、肿瘤坏死因子(TNF-α)均低于对照组,差异有统计学意义(P<0.05);治疗后,观察组APACHE-Ⅱ评分低于对照组,差异有统计学意义(P<0.05)。结论连续性血液净化治疗可降低弥漫性腹膜炎并发感染性休克患者的炎症反应和APACHE-Ⅱ评分,促进恢复。
Objective This paper aims to investigate the effect of continuous blood purification on inflammatory response,acute physiology and chronic health status scoreⅡ(APACHE-Ⅱscore)in patients with diffuse peritonitis complicated by septic shock.Methods The clinical data of 85 patients with diffuse peritonitis complicated by septic shock diagnosed and treated in our hospital from March 2017 to December 2019 were retrospectively analyzed.According to different treatment methods,the clinical data of 42 patients with basic treatment were classified as control.The clinical data of 43 patients who received basic treatment and continuous blood purification treatment were divided into observation group,and the inflammatory response and APACHE-Ⅱscore were compared between the two groups.Results After treatment,the serum procalcitonin(PCT),C-reactive protein(CRP),interleukin factor-8(IL-8),and tumor necrosis factor(TNF-α)in the observation group were all lower than those in the control group.Academic significance(P<0.05);After treatment,the observation group APACHE-Ⅱscore was lower than the control group,the difference was statistically significant(P<0.05).Conclusion Continuous blood purification treatment can reduce the inflammatory response and APACHE-Ⅱscore of patients with diffuse peritonitis complicated by septic shock,and promote recovery.
作者
吴俊
杨洋
WU Jun;YANG Yang(Department of General Surgery,Second People's Hospital of Yichun,Yichun Jiangxi 336000,China)
出处
《透析与人工器官》
2020年第3期28-29,33,共3页
Chinese Journal of Dialysis and Artificial Organs
作者简介
吴俊(1972-)男,本科,副主任医师。从事乳房良性肿物切除术及其他普外科疾病的诊治工作。
