期刊文献+

利伐沙班治疗静脉血栓栓塞症患者的临床疗效 被引量:4

Study on the clinical efficacy of rivaroxaban in the treatment of venous thromboembolism
在线阅读 下载PDF
导出
摘要 目的探讨利伐沙班治疗静脉血栓栓塞症(VTE)患者的临床疗效。方法选取赤峰市医院2017年09月至2019年06月收治70例VTE患者。根据抗凝药物不同分为对照组(n=34)和观察组(n=36)。比较两组患者治疗前后患侧肢体经皮氧分压(TcpO2);治疗后完全通畅率和血栓溶解有效率。结果治疗后,观察组患者的TcpO2高于对照组患者;完全通畅率为83.4%高于对照组患者55.9%,差异有统计学意义(P<0.05);对照组患者血栓溶解总有效率为79.41%低于观察组患者83.33%,差异无统计学意义。结论利伐沙班治疗VTE疗效优于传统抗凝药物且不增加不良事件的发生,值得临床推广使用。 Objective To explore the clinical effect of rivaroxaban in the treatment of venous thromboembolism(VTE).Method 70 VTE patients were admitted to Chifeng hospital from September 2017 to June 2019.According to different anticoagulants,they were divided into control group(n=34)and observation group(n=36).Transcutaneous oxygen partial pressure(TcPO2),patency rate and thrombolysis efficiency were compared before and after treatment.Result After treatment,TcPO2 in the observation group was higher than that in the control group;the complete patency rate was 83.4%higher than that in the control group 55.9%,the difference was statistically significant(P<0.05);the total effective rate of thrombolysis in the control group was 79.41%lower than that in the observation group 83.33%,the difference was not statistically significant.Conclusion Rivaroxaban is better than traditional anticoagulants in the treatment of VTE,and does not increase the incidence of adverse events.It is worthy of clinical application.
作者 党永康 乌兰 杨柳 姜学超 Dang Yongkang;Wu Lan;Yang Liu;Jiang Xuechao(Department of Vascular Surgery,Chifeng Municipal Hospital,Chifeng 024000,Inner Mongolia,China)
出处 《血管与腔内血管外科杂志》 2020年第3期213-216,共4页 Journal of Vascular and Endovascular Surgery
关键词 静脉血栓栓塞症 利伐沙班 抗凝治疗 venous thromboembolism rivaroxaban anticoagulant therapy
作者简介 党永康,主任,主任医师,主要从事血管外科静脉血栓等静脉疾病、动脉疾病的诊治,赤峰市医院;通信作者:乌兰,E-mail:wulan1992s@163.com
  • 相关文献

参考文献4

二级参考文献74

  • 1胡大一,张鹤萍,孙艺红,姜立清.华法林与阿司匹林预防非瓣膜性心房颤动患者血栓栓塞的随机对照研究[J].中华心血管病杂志,2006,34(4):295-298. 被引量:163
  • 2邹治鹏,何建国,程显声,赵彦芬,陈白屏,高莹,熊长明,倪新海,荆志诚.230例急性肺动脉血栓栓塞症患者对症治疗、抗凝治疗和溶栓治疗的住院转归[J].中国循环杂志,2006,21(3):219-221. 被引量:27
  • 3WolfeTR, AllenTL. Syncope as an emergency department presentation of pulmonary embolism[J]. J Emerg Med, 16(1):27–31.
  • 4KonstantinidesSV. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism[J]. Eur Heart J, 2014, 35(45): 3145–3146. DOI:10.1093/eurheartj/ehu393.
  • 5HeitJA. The epidemiology of venous thromboembolism in the community[J]. Arterioscler Thromb Vasc Biol, 2008,28(3):370–372.DOI: 10.1161/ATVBAHA.108.162545.
  • 6CohenAT, AgnelliG, AndersonFA, et al. Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality[J]. Thromb Haemost, 2007,98(4):756–764.
  • 7YangY, LiangL, ZhaiZ, et al. Pulmonary embolism incidence and fatality trends in chinese hospitals from 1997 to 2008: a multicenter registration study[J]. PLoS One, 2011,6(11):e26861.DOI: 10.1371/journal.pone.0026861.
  • 8LaporteS, MismettiP, DécoususH, et al. Clinical predictors for fatal pulmonary embolism in 15,520 patients with venous thromboembolism: findings from the Registro Informatizado de la Enfermedad TromboEmbolica venosa (RIETE) Registry[J]. Circulation, 2008,117(13):1711–1716.DOI: 10.1161/CIRCULATIONAHA.107.726232.
  • 9GoldhaberSZ, VisaniL, De RosaM. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER)[J]. Lancet, 1999,353(9162):1386–1389.
  • 10KyrlePA, RosendaalFR, EichingerS. Risk assessment for recurrent venous thrombosis[J]. Lancet, 2010,376(9757):2032–2039.DOI: 10.1016/S0140–6736(10)60962–2.

共引文献1883

同被引文献59

引证文献4

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部