摘要
目的探讨利伐沙班治疗静脉血栓栓塞症(VTE)患者的临床疗效。方法选取赤峰市医院2017年09月至2019年06月收治70例VTE患者。根据抗凝药物不同分为对照组(n=34)和观察组(n=36)。比较两组患者治疗前后患侧肢体经皮氧分压(TcpO2);治疗后完全通畅率和血栓溶解有效率。结果治疗后,观察组患者的TcpO2高于对照组患者;完全通畅率为83.4%高于对照组患者55.9%,差异有统计学意义(P<0.05);对照组患者血栓溶解总有效率为79.41%低于观察组患者83.33%,差异无统计学意义。结论利伐沙班治疗VTE疗效优于传统抗凝药物且不增加不良事件的发生,值得临床推广使用。
Objective To explore the clinical effect of rivaroxaban in the treatment of venous thromboembolism(VTE).Method 70 VTE patients were admitted to Chifeng hospital from September 2017 to June 2019.According to different anticoagulants,they were divided into control group(n=34)and observation group(n=36).Transcutaneous oxygen partial pressure(TcPO2),patency rate and thrombolysis efficiency were compared before and after treatment.Result After treatment,TcPO2 in the observation group was higher than that in the control group;the complete patency rate was 83.4%higher than that in the control group 55.9%,the difference was statistically significant(P<0.05);the total effective rate of thrombolysis in the control group was 79.41%lower than that in the observation group 83.33%,the difference was not statistically significant.Conclusion Rivaroxaban is better than traditional anticoagulants in the treatment of VTE,and does not increase the incidence of adverse events.It is worthy of clinical application.
作者
党永康
乌兰
杨柳
姜学超
Dang Yongkang;Wu Lan;Yang Liu;Jiang Xuechao(Department of Vascular Surgery,Chifeng Municipal Hospital,Chifeng 024000,Inner Mongolia,China)
出处
《血管与腔内血管外科杂志》
2020年第3期213-216,共4页
Journal of Vascular and Endovascular Surgery
关键词
静脉血栓栓塞症
利伐沙班
抗凝治疗
venous thromboembolism
rivaroxaban
anticoagulant therapy
作者简介
党永康,主任,主任医师,主要从事血管外科静脉血栓等静脉疾病、动脉疾病的诊治,赤峰市医院;通信作者:乌兰,E-mail:wulan1992s@163.com