摘要
目的探讨活血通络汤治疗下肢闭塞性动脉硬化的临床疗效。方法选取2017年5月至2019年10月首都医科大学石景山教学医院北京市石景山医院收治下肢闭塞性动脉硬化患者200例。根据用药方式不同分为观察组和对照组,各100例。比较治疗后两组患者临床疗效;比较治疗前后疼痛评分、冷感评分、麻木评分和间歇性跛行距离、纤维蛋白原指标和肝肾指标(谷丙转氨酶、天门冬氨酸氨基转移酶、尿素氮和血肌酐)。结果治疗后,观察组患者治疗总有效率高于对照组患者;疼痛评分、冷感评分、麻木评分低于对照组患者,间歇跛行距离长于对照组患者;纤维蛋白原、谷丙转氨酶、天门冬氨酸氨基转移酶、尿素氮和血肌酐均低于对照组患者,差异有统计学意义(P<0.05)。结论活血通络汤治疗下肢闭塞性动脉硬化疗效显著,且能够改善凝血及肝肾各项指标,值得研究和推广。
Objective To explore the therapeutic effect of Huoxue Tongluo decoction on lower extremity arteriosclerosis obliterans.Method 200 patients with occlusive arteriosclerosis of the lower extremities were selected from Shijingshan Teaching Hospital of Capital Medical University Beijing Shijingshan Hospital from May 2017 to October 2019.According to different types of medication,they were divided into observation group and control group,100 cases each.The clinical effects of the two groups were compared after treatment;pain score,cold sensation score,numbness score,intermittent claudication distance,fibrinogen index,liver and kidney index(alanine aminotransferase,aspartate aminotransferase,urea nitrogen and serum creatinine)were compared before and after treatment.Result After treatment,the total effective rate of the observation group was higher than that of the control group;the pain score,cold sensation score and numbness score were lower than those of the control group,and the intermittent claudication distance was longer than that of the control group;fibrinogen,alanine aminotransferase,aspartate aminotransferase,urea nitrogen and serum creatinine were lower than those of the control group,the difference was statistically significant(P<0.05).Conclusion Huoxue Tongluo decoction is effective in the treatment of arteriosclerosis obliterans of lower extremities,and can improve the blood coagulation,liver and kidney indicators,and is worthy of research and promotion.
作者
赵爱民
翟文静
Zhao Aimin;Zhai Wenjing(Department of Traditional Chinese Medicine,Shijingshan Teaching Hospital of Capital Medical University Beijing Shijingshan Hospital,Beijing 100043,China)
出处
《血管与腔内血管外科杂志》
2020年第5期419-423,共5页
Journal of Vascular and Endovascular Surgery
关键词
活血通络汤
闭塞性动脉硬化
疗效
Huoxue Tongluo decoction
arteriosclerosis obliterans
curative effect
作者简介
赵爱民,主治医师,主要从事糖尿病的中医治疗研究,首都医科大学石景山教学医院北京市石景山医院;通信作者:翟文静,E-mail:zwj20012006@126.com
