摘要
目的探讨斑块旋切术(DA)联合药物涂层球囊(DCB)在糖尿病足溃疡(DFU)合并严重下肢缺血(CLI)中的临床疗效。方法选取大庆油田总医院2017年1月至2018年12月收治66例DFU合并CLI患者,根据治疗方式不同分为观察组和对照组,各33例。比较两组患者溃疡愈合率、截肢率、溃疡愈合天数、术后12个月复发率、术后12个月行走距离。结果两组患者愈合率、截肢率和溃疡愈合天数比较,差异无统计学意义;观察组患者溃疡复发率低于对照组患者,术后12个月行走距离长于对照组患者,差异有统计学意义(P<0.05)。结论DA联合DCB在DFU合并CLI治疗中获得良好临床效果。
Objective To investigate clinical effect of debulking atherectomy(DA)combined with drug-coated balloons(DCB)in diabetic foot ulcer(DFU)with critical limb ischemia(CLI).Method Sixty six patients with DFU combined with CLI in Daqing Oilfield General Hospital from January 2017 to December 2018 were selected and divided into observation group and control group according to different treatment methods,with 33 cases in each group.The ulcer healing rate,amputation rate,ulcer healing days,recurrence rate at 12 months after operation and walking distance at 12 months after operation were compared between the two groups.Result There was no significant difference in the healing rate,amputation rate and ulcer healing days between the two groups;the ulcer recurrence rate in the observation group was lower than that in the control group,and the walking distance in 12 months after operation was longer than that in the control group(P<0.05).Conclusion DA combined with DCB in the treatment of DFU combined with CLI achieved good clinical effect.
作者
姜国忠
李蕾
李雪岩
崔凤奎
赵健飞
董智强
魏福庆
徐新
鹿凯
马琳
刘巍立
Jiang Guozhong;Li Lei;Li Xueyan;Cui Fengkui;Zhao Jianfei;Dong Zhiqiang;Wei Fuqing;Xu Xin;Lu Kai;Ma Lin;Liu Weili(Department of Vascular Surgery,Daqing Oil Field General Hospital,Daqing 163312,Heilongjiang,China;Department of Clinical Medicine,Daqing Medical College,Daqing 163312,Heilongjiang,China)
出处
《血管与腔内血管外科杂志》
2020年第5期457-459,466,共4页
Journal of Vascular and Endovascular Surgery
基金
黑龙江省基金资助(zdy-2016-068)
关键词
斑块旋切
药物涂层球囊
糖尿病足溃疡
严重下肢缺血
debulking atherectomy
drug-coated balloon
diabetic foot ulcer
critical limb ischemia
作者简介
姜国忠,副主任医师,主要从事血管疾病的研究,大庆油田总医院;通信作者:李蕾,E-mail:liyanleisix@126.com
