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基于《中国老年人潜在不适当用药判断标准》对本院老年慢性病患者多重用药的调查分析

Investigation and analysis about multiple drug use in elderly patients with chronic diseases in our hospital based on the judgment criteria for potentially inappropriate use of drugs for the elderly in China
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摘要 目的调查和分析本院老年慢性病患者多重用药所发生的潜在不适当用药(PIM)情况。方法采用回顾性研究方法,查阅并整理本院2019年-2020年住院治疗的192例老年慢性病患者的治疗用药方案,利用《中国老年人潜在不适当用药判断标准(2017年版)》评价老年慢性病患者的PIM情况,并应用Logistic回归分析法分析发生PIM的影响因素。结果192例老年慢性病患者中有79例存在PIM,占比41.14%,涉及357个风险点。PIM中A级警示药物10种,共计94例次,B级警示药物7种,共计22例次。Logistic回归分析结果显示,本院老年慢性病患者PIM与年龄、住院次数、药物种类和共患病等因素呈显著性相关(P<0.05)。结论老年慢性病患者中普遍存在PIM现象,《中国老年人潜在不适当用药判断标准》可对老年人用药情况进行筛查,降低PIM发生率。临床药师应注意加强药学宣教,提高老年患者安全、合理用药意识。 Objective To investigate and analyze the potentially inappropriate medication(PIM)in elderly patients who had chronic diseases.Methods The 192 elderly hospitalized patients with chronic diseases in our hospital from 2019 to 2020 were consulted and sorted out their therapeutic schemes through retrospective research method.The PIM of elderly patients with chronic diseases were evaluated by using The Judgment Criteria for Potentially Inappropriate Use of Drugs for the Elderly in China(2017 Edition).Besides,the influencing factors of PIM were analyzed by Logistic regression analysis.Results Among 192 elderly patients with chronic diseases,79 of them had PIM which accounting for 41.14%and involving 357 risk points.PIM refers to 10 types of A classification waring drugs with a total of 94 cases and 7 types of B classification waring drugs with a total of 22 cases.Logistic regression analysis showed that the PIM of elderly patients with chronic diseases in our hospital were significantly correlated with factors such as age,hospitalization frequency,drug species and comorbidities(P<0.05).Conclusion PIM is a common phenomenon in elderly patients with chronic diseases.The elderly medications could screen and reduce the incidence of PIM according to The Judgment Criteria for Potentially Inappropriate Use of Drugs for the Elderly in China.Clinical pharmacists should pay attention to strengthening pharmacy education and improve the awareness of safe and rational drug administration among elderly patients.
作者 施洋 陈振东 党晓玲 张红英 列莲丽莎 秦荣 SHI Yang;CHEN Zhendong;DANG Xiaoling;ZHANG Hongying;Lielian Lisha;QIN Rong(Integrated Traditional Chinese and Western Medicine hospital of Karamay,Karamay,834000,Xinjiang,China;Peoples'Hospital of Karamay,Karamay,834000,Xinjiang,China)
出处 《新疆医学》 2023年第6期715-718,749,共5页 Xinjiang Medical Journal
基金 克拉玛依市人民医院院级科研项目(项目编号:Ry2018008)
关键词 老年患者 慢性疾病 多重用药 潜在不适当用药 合理用药 Elderly patients Chronic diseases Multiple drug use Potential inappropriate medication Rational drug administration
作者简介 施洋,男,硕士,主管药师,研究方向:临床药学、心血管药理学;通信作者:秦荣,女,硕士,主治医师,研究方向:中医内科学。E-mail:qinrong_xj@126.com。
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