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急诊脓毒症患者血清NT-pro BNP和β2-MG水平及临床意义

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摘要 目的探究急诊脓毒症患者血清N端脑利钠肽前体(NT-pro BNP)、β2-微球蛋白(β2-MG)水平表达及临床意义。方法采取回顾性选取2016年6月~2021年2月我院急诊科诊治的脓毒症患者66例,根据患者病情程度将其分为脓毒症组(n=30)、严重脓毒症组(n=21)、感染性休克组(n=15)。比较各组患者的血清NT-pro BNP、D-二聚体(D-D)和β2-MG水平并分析各指标在急诊脓毒症患者病情及预后评估价值。结果血清NT-pro BNP、D-D和β2-MG水平:感染性休克组高于严重脓毒症组,差异有统计学意义(P<0.05);APACHEⅡ和SOFA评分:感染性休克组显著低于严重脓毒症患者,差异有统计学意义(P<0.05);血清NT-pro BNP、D-D和β2-MG水平:严重脓毒症组显著高于脓毒组,差异有统计学意义(P<0.05);APACHEⅡ和SOFA评分:严重脓毒症组患者显著低于脓毒症患者,差异有统计学意义(P<0.05)。结论血清NT-pro BNP、D-D和β2-MG水平能够有效评估脓毒症患者病情及预后,具有重要的临床意义。
作者 李健
出处 《西藏医药》 2021年第6期72-74,共3页 Tibetan Medicine
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