摘要
目的分析二次电切术治疗非肌层浸润性膀胱癌效果和导致手术复发的影响因素。方法选择在该院进行治疗的98例非肌层浸润性膀胱癌病患为研究样本,其治疗时间均在2017年9月至2018年9月,依据病患实施电切手术次数将其分成常规组(56例)以及实验组(42例)。常规组病患均实施初次电切术治疗,实验组病患均实施二次电切术治疗。手术后观察病患复发情况,对比两组治疗效果、复发率以及手术前后生活质量得分。收集全部病患临床资料,分别对比复发病患与未复发病患临床资料,采用Logistic回归方程分析肿瘤复发影响因素。结果实验组与常规组总有效率分别是83.33%、64.29%,实验组与常规组复发率分别是7.14%、17.86%,两组比较差异均有统计学意义(P<0.05);手术后实验组病患在社会能力、生理职能、心理健康、生理能力、生活积极性、情感职能、机体疼痛以及总分方面得分均高于常规组(P<0.05)。复发组与未复发组在二次治疗、肿瘤数量、肿瘤直径、肿瘤分期以及肿瘤分级方面差异有统计学意义(P<0.05)。研究发现电切次数、肿瘤直径以及肿瘤分级是疾病复发的危险因素,电切次数、肿瘤直径以及肿瘤分期是疾病进展的危险因素。结论膀胱癌病患实施二次电切术治疗可减少初次手术后肿瘤残留情况,可有效预防肿瘤复发,提升疾病预后。
【Objective】To analyze the effect of secondary resection in the treatment of non-muscle invasive bladder cancer and the influencing factors of recurrence.【Methods】Ninety-eight cases of non-myometrial invasive bladder cancer patients who were treated in our hospital were selected as the study samples.The treatment time was between September 2017 and September2018.According to the number of electrosurgical operations,the patients were divided into the conventional group(56 cases)and the experimental group(42 cases).The patients in the conventional group were treated with primary electrotomy,while those in the experimental group were treated with secondary electrotomy.After operation,the recurrence of patients was observed,and the treatment effect,recurrence rate and quality of life scores before and after operation were compared in each group.The clinical data of all patients were collected,and the clinical data of relapsed patients and non-relapsed patients were compared.The influencing factors of tumor recurrence were analyzed by logistic regression equation.【Results】The total effective rates of the experimental group and the conventional group were 83.33%and 64.29%respectively,the recurrence rates of the experimental group and the conventional group were 7.14%and 17.86%respectively,and the differences were statistically significant(P<0.05).The scores of social ability,physiological function,mental health,physiological ability,life enthusiasm,emotional function,body pain and total score in the experimental group were higher than those in the conventional group(P<0.05).There were significant differences in the second treatment,tumor number,tumor diameter,tumor stage and tumor grade between the recurrence group and the non-recurrence group(P<0.05).It was found that the number of resection,tumor diameter and tumor grade were the risk factors of disease recurrence,and the number of resection,tumor diameter and tumor stage were the risk factors of disease progression.【Conclusion】The second resection can reduce the residual tumor after the first operation,effectively prevent tumor recurrence and improve the prognosis of bladder cancer patients.
作者
王晓灵
刘永波
张锋
赵彦荣
周士强
WANG Xiaoling;LIU Yongbo;ZHANG Feng;ZHAO Yanrong;ZHOU Shiqiang(Department of Urinary Surgery,Tangta Hospital of Yuncheng County,Yuncheng,Shandong 274700,China)
出处
《中国医学工程》
2020年第2期39-43,共5页
China Medical Engineering
关键词
危险因素
膀胱肿瘤
二次电切术
复发
非肌层浸润性膀胱癌
进展
risk factors
bladder tumor
secondary resection
recurrence
non-muscular invasive bladder cancer
progress
