摘要
绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)是原发性骨质疏松症最常见的类型,是威胁中老年女性身体健康最常见的疾病之一。绝经后雌激素水平骤降,造成脂骨代谢失调,是PMOP发病的重要机制。人体内血脂含量丰富,血脂异常与骨密度下降密切相关,尤其是总胆固醇,其失调会导致骨质疏松和动脉粥样硬化等代谢性疾病发生。因此,本文就胆固醇在PMOP防治中的作用进行综述,以期为PMOP诊疗提供新思路。
Postmenopausal osteoporosis(PMOP)is the most common type of primary osteoporosis and one of the most common diseases that threaten the health of middleaged and elderly women.The sudden drop of estrogen level after menopause leads to the imbalance of fat and bone metabolism,which is an important mechanism of PMOP.The human body is rich in blood lipids,and dyslipidemia is closely related to the decline of bone mineral density,especially total cholesterol,whose imbalance will lead to metabolic diseases such as osteoporosis and atherosclerosis.Therefore,this article reviews the role of cholesterol in the prevention and treatment of PMOP in order to provide new ideas for the diagnosis and treatment of PMOP.
作者
韦凤旭
林青
韦安达
卢长巍
Wei Fengxu;Lin Qing;Wei Anda;Lu Changwei(Graduate School of Youjiang Medical College for Nationalities,Baise 533000;Guangxi Key Laboratory of Zhuang and Yao Ethnic Medicine,Nanning 530200,China;Baise Center for Disease Control and Prevention,Baise 533000;Guangxi university of chinese medicine,Nanning 530200;Department of Spinal Osteopathy,Hechi People’s Hospital,Hechi 547000;Collaborative Innovation Center of Zhuang and Yao Ethnic Medicine,Nanning 530200,China;Guangxi Zhuang Autonomous Region Ethnic Medicine Resources and Application Engineering Research Center,Nanning 530200,China)
出处
《壮瑶药研究》
2023年第2期365-368,共4页
Research of Zhuang and Yao Ethnic Medicine
基金
广西骨与关节退行性疾病基础研究与转化重点实验室项目基金(21-220-06)
2022年右江民族医学院研究生创新计划项目(YZCXJH2022004)
广西中医药重点学科壮药学(GZXK-Z-20-64)
关键词
绝经后骨质疏松
胆固醇
脂骨代谢
postmenopausal osteoporosis
cholesterol
fat bone metabolism
作者简介
第一作者:韦凤旭,在读硕士研究生,研究方向:骨科学;通信作者:卢长巍,主任医师;韦安达,助教,研究方向:中药(壮瑶药)鉴定与开发
