摘要
Three-dimensional printing is a technology that prints the products layer-by-layer,in which materials are deposited according to the digital model designed by computer aided design(CAD)software.This technology has competitive advantages regarding product design complexity,product personalization,and on-demand manufacturing.The emergence of 3 D technology provides innovative strategies and new ways to develop novel drug delivery systems.This review summarizes the application of 3 D printing technologies in the pharmaceutical field,with an emphasis on the advantages of 3 D printing technologies for achieving rapid drug delivery,personalized drug delivery,compound drug delivery and customized drug delivery.In addition,this article illustrates the limitations and challenges of 3 D printing technologies in the field of pharmaceutical formulation development.
基金
supported by the National Science and Technology Major Project which belongs to“The research on the key technology of 3D printing techniques in the field of pharmaceutical preparation”(No.2017ZX09201-003-011,China)
supported by the China Pharmaceutical Association-Yiling Biomedical Innovation Project(China)
financial and instrumental support from Jingxin Pharmaceutical Co.,Ltd.(Zhejiang,China)
作者简介
Corresponding author:Pingtian Ding,Tel./fax:+8602443520515,E-mail:dingpingtian@qq.com;Corresponding author:Weisan Pan,Tel./fax:+8602443520533,E-mail:ppwwss@163.com;Equal contributions:Mengsuo Cui;Equal contributions:Hao Pan