摘要
目的分析2012—2021年山东省青岛市围产儿出生缺陷情况,为综合防治提供依据。方法通过收集2012—2021年山东省青岛市辖区接产医院围产儿出生缺陷监测资料,采用χ^(2)检验或趋势χ^(2)检验对出生缺陷情况进行统计分析。结果2012—2021年山东省青岛市围产儿出生缺陷平均发生率为78.83/万,10年间出生缺陷发生率有所上升(χ^(2)_(趋势)=211.87,P<0.001);围产儿出生缺陷男性(86.73/万)高于女性(69.85/万),城镇(123.88/万)高于农村(40.83/万),差异均有统计学意义(χ^(2)=94.71,P<0.001;χ^(2)=2275.238,P<0.001);出生缺陷发生率在不同年龄组产妇中比较差异有统计学意义(P<0.001)。2012—2021年山东省青岛市前5位出生缺陷依次为先天性心脏病、多指(趾)、并指(趾)、总唇裂、外耳其他畸形。结论2012—2021年山东省青岛市出生缺陷率上升,先天性心脏病一直位于出生缺陷首位,出生缺陷与围产儿性别、城乡分布、产妇年龄有关。应加强宣教,提倡适龄生育,关注环境暴露与遗传因素,探索降低出生缺陷发生率的有效途径和方法。
Objective To analyze the situation of perinatal birth defects in Qingdao,Shandong Province from 2012 to 2021,and to provide basis for comprehensive prevention and treatment.Methods Hospital surveillance data of perinatal birth defects in Qingdao,Shandong Province from 2012 to 2021 were collected,χ^(2)test andχ^(2)trend test were used for statistical analysis.Results The average incidence rate of birth defects was 78.83/10000 in Qingdao,Shandong Province from 2012 to 2021,showing an upward trend(χ^(2)_(trend)=211.87,P<0.001).The incidence of perinatal birth defects in male(86.73/10000)was higher than that in female(69.85/10000),while this number in urban area(123.88/10000)was higher than that in rural area(40.83/10000),and the differences were statistically significant(χ^(2)=94.71,P<0.001;χ^(2)=2275.238,P<0.001).There were significant differences in the incidence of birth defects among different age groups(P<0.001).The top five birth defects were congenital heart disease,hyprdactylia,symphysodactylia,total cleft lip,and other deformities of the external ear in Qingdao from 2012 to 2021.Conclusion The rates of birth defect have been increasing in Qingdao,Shandong Province from 2012 to 2021.Congenital heart disease has always been the top 1 birth defect,and birth defects are related to perinatal gender,urban-rural distribution,and maternal age.Therefore,advocacy should be strengthened,age-appropriate childbearing should be encouraged,attention should be paid to environmental exposure and genetic factors,so as to explore effective ways to reduce the high incidence of birth defects.
作者
陈玉华
葛翠翠
尹亚童
袁丽
CHEN Yu Hua;GE Cui Cui;YIN Ya Tong;YUAN Li(Maternal and Child Health Care and Family Planning Service Center of Qingdao,Qingdao 266000,Shandong Province,China)
出处
《中国妇幼卫生杂志》
2022年第4期53-57,共5页
Chinese Journal of Women and Children Health
关键词
围产儿
出生缺陷
发生率
perinatal infant
birth defect
incidence
作者简介
通信作者:袁丽,Email:yuanli1969@163.com
