摘要
肌力下降、肌痛是皮肌炎常见的临床症状,及时、正确的肌力评估对于判断疾病活动度和制定治疗方案都十分重要。目前对于肌炎的常规治疗以糖皮质激素、免疫抑制剂等为主,部分患者因对药物治疗不应答导致肌力恢复缓慢甚至无明显好转,更有部分患者因长期使用糖皮质激素出现激素性肌炎、感染、骨质疏松等不良反应。药物治疗以外的康复治疗被认为是皮肌炎患者恢复运动功能的有效手段。因此,正确的肌力评估及合理的康复治疗,有助于改善皮肌炎患者的肌肉症状,提高患者的生活质量,减少药物治疗带来的不良反应。
Decreased muscle strength and muscle soreness are common clinical symptoms of dermatomyositis. Muscle strength assessment timely and correctly is vital for diagnosis and treatment of dermatomyositis. At present, conventional treatment mainly includes glucocorticoids and immunosuppressants, however, the muscle strength of some patients recovers slowly or has no significant improvement due to the lack of response to the medication. Some patients even have adverse reactions such as steroid myositis, infection, or osteoporosis due to long-term use of glucocorticoids. Therefore, rehabilitation is considered to be an effective means to restore motor function in patients with dermatomyositis. Correct muscle strength assessment and designed rehabilitation are helpful to improve the muscle symptoms and quality of life of patients with dermatomyositis and reduce the adverse reactions caused by drug.
作者
朱子聪
金凌
王子璇
赵佳
宋小慧
曹华
ZHU Zicong;JIN Ling;WANG Zixuan;ZHAO Jia;SONG Xiaohui;CAO Hua(Department of Dermatology,Ruijin Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200025,China;Department of Rehabilitation,Ruijin Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200025,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2022年第12期1350-1355,共6页
The Chinese Journal of Dermatovenereology
基金
国家自然科学基金面上项目(81573037,81872523,82073432)
国家临床重点专科建设项目(2012649)
上海市科委医学引导类项目(134119a6100)
上海申康医院发展中心临床创新三年行动计划(16CR3084B)
上海交通大学医学院高峰学科——临床医学研究型医师(20172009)
上海市医苑新星青年医学人才培养资助计划杰出青年医学人才类(2019)
关键词
皮肌炎
肌肉损伤
肌力评估
康复治疗
Dermatomyositis
Muscle injury
Muscle strength assessment
Rehabilitation therapy
作者简介
朱子聪,金凌对本文的贡献相同;金凌,朱子聪对本文的贡献相同;通信作者:曹华,E-mail:drcaohua@126.com;通信作者:宋小慧,E-mail:songxiaomo2012@126.com
