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生物标志物对ARDS预后的评估

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摘要 急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)是由各种肺内和肺外致病因素所导致的以弥漫性肺泡损伤为病理特征,以难治性低氧血症为临床特征的综合征。ARDS最早于1967年由Ashbaugh[1]等报道,1994年美欧联席会议(American?European consensus definition,AECC)初次提出具体的诊断标准[2],2011年在此基础上提出了更为精准的ARDS柏林定义[3],并根据氧合指数将ARDS分为轻、中、重三级,随疾病严重程度的增加,病死率也相应增加;2016年大规模的流调研究[4]显示ARDS住院死亡率仍高达46%。
出处 《中国呼吸与危重监护杂志》 CAS CSCD 2024年第8期587-592,共6页 Chinese Journal of Respiratory and Critical Care Medicine
基金 国家自然科学基金(81870072) 国家重点研发计划(2020YFC2003705) 中央高水平医院临床业务费专项临床研究项目(2022-NHLHCRF-LX-01-0105) 中国医学科学院医学与健康科技创新工程(2022-I2M-JB-016)
作者简介 通信作者:黄絮,Email:huangxu1122@sina.com
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