摘要
目的探索体质量指数对肺栓塞患者临床特点与生存状况的影响。方法选取2014年5月至2017年6月于义乌市中心医院接受治疗的186例肺栓塞患者为研究对象,按照体质量指数将患者分为3组即正常组、超重组和肥胖组。检测并比较3组患者的相关实验指标和临床症状,比较患者的分级情况以及存活率。结果正常组患者的红细胞压积(35.14±7.26)%、血红蛋白(122.03±21.47)g/L、尿酸(296.23±12.47)μmol/L低于超重组和肥胖组患者,差异有统计学意义(F=4.214、4.412、4.571,P=0.043、0.038、0.036)。正常组的总胆红素(16.04±12.31)μmol/L高于超重组和肥胖组患者,差异有统计学意义(F=4.183,P=0.045)。正常组患者的咳嗽率28.95%、呼吸困难率55.26%低于超重组和肥胖组患者,差异有统计学意义(χ~2=3.916、4.876,P=0.047、0.032)。超重组患者的胸痛发生率为33.33%高于正常组26.32%和肥胖组患者13.16%,而下肢肿胀发生率高于正常组和超重组患者,差异有统计学意义(χ~2=7.329、15.286,P=0.014、0.001)。正常组患者的抗凝药物使用率81.58%低于超重组94.44%和肥胖组患者94.74%,差异有统计学意义(χ~2=5.439,P=0.022)。超重组患者的存活率97.22%高于正常组85.53%和肥胖组患者94.74%,数据差异有统计学意义(χ~2=4.886,P=0.040)。结论体质指数与肺栓塞患者病情的危急程度无明显关联,但较高体质量指数患者的红细胞压积、血红蛋白以及尿酸水平较高,抗凝药物的使用率也较高。肥胖的肺栓塞患者存活率相对较高,具有较好的预后效果。
Objective To discuss the association of body mass index(BMI)with clinical features and survival rate of patients with pulmonary embolism.Methods 186 patients with pulmonary embolism treated in our hospital from May 2014 to June 2017 were enrolled and divided into 3 groups based on their BMI,as normal group(n=76),overweight group(n=72)and obese group(n=38).The related laboratory parameters,clinical symptoms and survival rate of the three groups were compared.Results The levels of hematocrit(35.14±7.26%),hemoglobin(122.03±21.47)g/L and uric acid(296.23±12.47)umol/L in the normal group were significantly lower than those in the overweight group and obese group(F=4.214,4.412,4.571,P=0.043,0.038,0.036),while the serum level of total bilirubin(16.04±12.31 umol/L)was significantly higher(P<0.05).The overall cough rate and dyspnea rate in the normal group were 28.95%and 55.26%,which were significantly lower than those in the overweight group and obese group(P<0.05).The incidence of chest pain in overweight group(33.33%)was significantly higher than that in normal group(26.32%)and obese group(13.16%),while the incidence of lower limb swelling was significantly higher in overweight group than that in normal group and obese group(χ~2=7.329,5.286,P=0.014,0.027).81.58%of patients in the normal group received anticoagulant treatment,which was significantly lower than that in the overweight group(94.44%)and the obese group(94.74%)(χ~2=5.539,P=0.022).The survival rate of overweight patients was 97.22%,which was significantly higher than that of normal group(85.53%)and obese group(94.74%)(χ~2=4.886,P=0.040).Conclusions There is no significant association between BMI and the severity of pulmonary embolism,however,patients with higher BMI usually have higher levels of hematocrit,hemoglobin and uric acid,and higher usage rate of anticoagulants..Obese patients with pulmonary embolism have relatively higher survival rate and better clinical outcome.
作者
吴洪
WU Hong(Yiwu Central Hospital,Yiwu,Zhejiang 322000,China)
出处
《中国预防医学杂志》
CAS
CSCD
2020年第5期580-583,共4页
Chinese Preventive Medicine
关键词
体质量指数
肺栓塞
临床特点
生存状况
Body mass index
Pulmonary embolism
Clinical characteristics
Survival status
作者简介
通信作者:吴洪,硕士研究生,主治医师,主要从事呼吸内科工作,E-mail:5404511202@qq.com
