摘要
目的分析宁波市≥25岁居民高胆固醇(total cholestrol,TC)水平对心脑血管疾病死亡和期望寿命的影响。方法使用宁波市2015年成人慢性病监测血清TC水平计算人群归因分值(population attribntable fration,PAF),采用2015年死因监测资料和人口统计数据估算血清高TC相关疾病归因死亡人数和对期望寿命的影响。结果2015年宁波市≥25岁居民血清TC水平为(4.92±0.97)mmol/L,男性血清TC水平(4.89±0.96)mmol/L低于女性(4.93±0.98)mmol/L,城市地区(4.91±0.95)mmol/L与农村地区(4.92±0.99)mmol/L居民血清TC水平基本一致,不同性别及地区居民血清TC水平差异均无统计学意义。归因于血清高TC的死亡人数1139人,占全部死亡人数的2.97%;缺血性心脏病和缺血性脑卒中归因于血清高TC的死亡人数分别为771人和368人,PAF分别为33.25%和11.61%。血清高TC导致宁波市期望寿命损失0.27岁,女性0.29岁高于男性0.25岁,城市地区期望寿命损失与农村地区一致均为0.27岁。结论宁波市血清高TC水平导致缺血性心脏病和缺血性脑卒中死亡,对女性期望寿命的影响大于男性。
Objective To discuss the effect of high serum total cholesterol(TC)levels on mortality and life expectancy among adults aged 25 years and above in Ningbo.Methods We used the data of serum TC level from the adult chronic disease surveillance in Ningbo in 2015 to calculate the population attribution fraction(PAF).The death monitoring data and demographic data were applied to estimate high serum TC related death number and loss in life expectancy.Results In 2015,the median serum TC level was(4.92±0.97)mmol/L among adults aged 25 and above in Ningbo,which was lower in males(4.89±0.96)mmol/L than in females(4.93±0.98)mmol/L.There was no significant difference in the serum TC level between subjects in urban area(4.92±0.99)mmol/L and in rural area(4.91±0.95)mmol/L,as well as between men and women.There were total 1139 high serum TC related deaths in Ningbo in 2015,accounting for 2.97%of all deaths,771 died from ischemic heart disease and 368 from ischemic stroke,with the PAF of 33.25%and 11.61%,respectively.The overall loss of life expectancy caused by high serum TC in Ningbo was 0.27 years,which was higher in females(0.29 years)than in males(0.25 years)and was no difference in urban and rural adults.Conclusions High serum TC level may cause death from ischemic heart disease and ischemic stroke,with higher life expectancy loss in females than in males.
作者
冯伟
王永
李思萱
毛书奇
龚清海
朱银潮
张良
李辉
刘世炜
FENG Wei;WANG Yong;LI Si-xuan;MAO Shu-qi;GONG Qing-hai;ZHU Yin-chao;ZHANG Liang;LI Hui;LIU Shi-wei(Fenghua District Center for Disease Control and Prevention,Ningbo,Zhengjiang 315000,China)
出处
《中国预防医学杂志》
CAS
CSCD
2020年第7期721-725,共5页
Chinese Preventive Medicine
基金
国家自然科学基金面上项目(81872721)
国家重点研发计划专项基金资助项目(2018YFC1315305)
关键词
胆固醇
人群归因分值
归因死亡人数
期望寿命
Cholesterol
Population attributable fraction
Attributed death
Life expectancy
作者简介
冯伟,硕士研究生,副主任医师,主要从事慢性非传染性疾病预防与控制工作;通信作者:李辉,E-mail:lihui4329@163.com
