摘要
目的探究自主性动机对抑郁症病情与临床治疗效果的影响,旨在提高抑郁症患者的生活质量水平。方法选取2016年6月~2018年6月于绍兴市第七人民医院接受治疗的90例抑郁症患者为研究对象,按照行为趋近和抑郁系统量表评分将所有患者分为两组,其中观察组患者43例,BAS/BIS评分为3~4分;对照组患者47例,BAS/BIS评分为1~2分;比较两组患者治疗前后的汉密尔顿抑郁量表(HAMD)评分、匹兹堡睡眠质量指数量表(PSQI)评分、血清脑源性神经营养因子(BDNF)水平。结果两组患者治疗前HAMD评分、PSQI评分以及血清BDNF水平差异无统计学意义(P>0.05);观察组患者治疗后HAMD评分为(18.14±2.11)分、PSQI评分为(4.22±0.55)分,对照组患者治疗后HAMD评分为(23.61±3.02)分、PSQI评分为(7.07±0.82)分,差异有统计学意义(P<0.05);观察组患者治疗后BDNF水平为(20.41±1.55)μg/L,对照组患者治疗后BDNF水平为(15.31±1.28)μg/L,差异有统计学意义(P<0.05);治疗总有效率患者为90.70%,对照组患者为80.85%,差异有统计学意义(P<0.05)。结论自主性动机在抑郁症患者的治疗过程中有积极作用,能够改善患者的抑郁症状和睡眠质量,提高临床治疗效果。
Objective To describe the effect of intrinsic motivation on clinical outcomes of patients with depression.Methods A total of 90 patients with depression treated in our hospital from June 2016 to June 2018 were enrolled and were divided into two groups based on the scores of BAS/BIS.43 patients with BAS/BIS score of 3-4 were assigned in the observation group,while 47 patients with BAS/BIS score of 1-2 were in the control group.Patients in the observation group received intrinsic motivation intervention for 6 weeks on top of routine treatment,which was given to those in the control group.The scores of Hamilton′s depression scale(HAMD)and the Pittsburgh sleep quality index(PSQI)as well as the serum level of brain-derived neurotrophic factor(BDNF)before and after the intervention were compared between the two groups.Results There were no significant differences in HAMD score,PSQI score and in the serum BDNF level between the two groups before the treatment(P>0.05).However,after the intervention,the HAMD score and HAMD score in the observation group were significantly lower compared to the control group(6.14±2.11 vs 13.61±3.02;4.22±0.55 vs 7.07±0.82;P<0.05).The serum BDNF level in the observation group was 20.41±1.55 ng/ml,which was higher than that of 15.31±1.28 ng/ml in the control group,the difference was statistically significant(P<0.05).The overall effective rate was significantly higher in the observation group than that in the control group(90.70%vs 80.85%,P<0.05).Conclusions Intrinsic motivation intervention plays an important role in the clinical outcomes of patients with depression by improving the symptoms and sleep quality.
作者
钱超
梁胜林
陈军良
李添红
QIAN Chao;LIANG Sheng-lin;CHEN Jun-liang;LI Tian-hong(Department of Severe Psychiatry,Shaoxing Seventh People′s Hospital,Shaoxing,Zhejiang 312000,China;不详)
出处
《中国预防医学杂志》
CAS
CSCD
2020年第9期1043-1046,共4页
Chinese Preventive Medicine
作者简介
通信作者:钱超,本科,主治医师,在职在读研究生,主要从事重症精神疾病研究,E-mail:puyayi8830@163.com
