摘要
目的探讨不同手术方式治疗ⅠA2~ⅡA2期宫颈癌的有效性。方法选取2015年4月至2018年8月间大连市瓦房店第二医院收治的行手术治疗的96例ⅠA2~ⅡA2期宫颈癌患者,采用随机数字表法分为观察组和对照组,每组48例。观察组患者行腹腔镜下子宫广泛性切除术和淋巴结清扫术(TLRH+LND),对照组患者行开腹子宫广泛性切除术和淋巴结清扫术(ARH+LND),比较两组患者手术基本情况、治疗效果及术后并发症发生情况。结果观察组患者术中出血量、术中输液量、术后排气时间、手术时间、肠道功能恢复时间和术后住院时间均少于对照组,术中尿量和淋巴结切除数均大于对照组,差异均有统计学意义(均P<0.01)。观察组患者有效率为91.7%,高于对照组的72.9%,差异有统计学意义(P<0.01)。观察组患者并发症有泌尿系统感染、尿瘘和膀胱功能障碍,发生率为6.3%;对照组患者并发症有神经损伤、切口感染、泌尿系统感染、尿瘘、肠梗阻和膀胱功能障碍,发生率为18.8%,两组比较,差异有统计学意义(P<0.01)。结论ⅠA2~ⅡA2期子宫颈癌患者采用TLRH+LND手术,有较高的安全性,创伤较小,术后恢复时间较短,术后并发症发生率较低,治疗效果较好,能替代ARH+LND手术,值得临床推广。
Objective To analyze the effectiveness of two different surgical methods in the treatment of stage IA2 to IIA2 cervical cancer.Methods Ninety-six patients with stage IA2 to IIA2 cervical cancer who underwent surgery at Wafangdian Second Hospital from April 2015 to August 2018 were enrolled.The patients were divided into an observation group and a control group by random number table method with 48 patients in each group.Patients in the observation group underwent laparoscopic radical hysterectomy plus lymph node dissection(TLRH+LND),and patients in the control group underwent abdominal radical hysterectomy plus lymphadenectomy(ARH+LND).The general conditions of the operation,the therapeutic efficacy and the complications after the operation were compared.Results Intraoperative blood loss,intraoperative transfusion volume,postoperative venting time,operation time,intestinal function recovery time,and postoperative hospital stay were significantly less in the observation group than in the control group(all P<0.05).The amount of urine and number of lymph node removed were higher in the observation group than in the control group(all P<0.05).The treatment efficacy rate was 91.7%in the observation group,which was significantly higher than 72.9%of the control group(P<0.05).The incidence of complication including urinary tract infection,urinary fistula and bladder dysfunction was 6.3%in the observation group.The incidence of complication including nerve damage,wound infection,urinary tract infection,urinary fistula,intestinal obstruction and bladder dysfunction was 18.8%in the control group.There was significant differences between the two groups(all P<0.05).Conclusion TLRH+LND surgery for IA2~IIA2 cervical cancer has high safety,few trauma,short postoperative recovery time,which significantly improves treatment efficacy with low incidence of postoperative complications.It can be used as an alternative to ARH+LND surgery and it is worthy of clinical promotion and application.
作者
吴秋艳
徐慧
WU Qiu-yan;XU Hui(Department of Obstetrics and Gynecology,Wafangdian Second Hospital,Dalian 116314,China;Department of Obstetrics,Affiliated Hospital of Jiangsu University,Zhenjiang 212001,China)
出处
《中国肿瘤临床与康复》
2020年第2期204-206,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
宫颈肿瘤
腹腔镜
子宫切除术
淋巴结清扫术
Cervical neoplasms
Laparoscopy
Hysterectomy
Lymph node dissection
作者简介
吴秋艳,女,副主任医师,主要从事妇科专业。
