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辅助生殖技术对子代出生结局影响的回顾性分析 被引量:1

Retrospective Analysis of Influence of Assisted Reproductive Technology on Birth Outcome of Offspring
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摘要 目的通过对辅助生殖技术妊娠结局和子代出生结局进行回顾性分析,探讨ART技术对妊娠结局和子代出生结局的影响。方法选取2014年1月至2019年12月在北京儿童医院顺义妇儿医院进行常规产检并接受过ART治疗的女性为病例组,选取同期正常妊娠的女性进行对照,按照与ART组女性末次月经在1个月以内、在同一年龄段选择对照人群,并随访对照组直到妊娠结局发生,将正常妊娠结局的女性作为最终的对照。采用SPSS19.0软件对数据进行统计学分析,采用均数±标准差(■±s)对计量资料进行描述,采用独立样本t检验比较组间差异;对计数资料采用率进行描述,卡方检验进行组间比较,P<0.05为差异具有统计学意义。结果子代出生结局如新生儿平均出生体重、低体重儿发生率等方面均具有显著性差异。双胎活产ART组与自然妊娠组在子代出生结局方面无显著性差异。结论ART技术在一定程度上会对妊娠结局及子代出生结局产生影响。 Objective Through retrospective analysis of pregnancy outcome and offspring birth outcome of assisted reproductive technology,to explore influence of ART technology on pregnancy outcome and offspring birth outcome.Methods The paper chose women with routine obstetric check-ups and treated with ART treatment at Beijing Children’s Hospital Shunyi Women’s and Children’s Hospital from January 2014 to December 2019 as case group,and women with normal pregnancy during the same period as control group.The author carried on statistical analysis on data with SPSS19.0 software,described measurement data with mean standard deviation(s),compared difference between groups with independent sample t test;described use rate of count data,and compared between groups with chi-square test,P<0.05,difference was statistically significant.Results Birth outcomes of offspring,such as average birth weight of newborns,incidence of low birth weight infants,showed significant difference.There was no significant difference between twin live birth ART group and natural pregnancy group in terms of offspring outcome.Conclusion ART technology may affect pregnancy outcome and birth outcome of offspring to a certain extent.
作者 张晓芬 ZHANG Xiao-fen(Shunyi District Maternity and Child Health Hospital,Beijing,101300)
出处 《智慧健康》 2021年第9期67-69,共3页 Smart Healthcare
关键词 辅助生殖技术 妊娠结局 出生缺陷 Assisted reproductive technology Pregnancy outcome Birth defects
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