摘要
目的探讨盐酸舍曲林联合心理治疗对脑卒中后抑郁患者的临床疗效。方法选取我院神经内科2019年9月至2020年9月接收的106例脑卒中后抑郁患者作为观察对象,进行回顾性分析。根据治疗方案差异分为研究组53例与对照组53例。对照组给予取舍林,研究组在此基础上联合心理治疗,比较两组患者HAMD-17评分、NIHSS评分与Barthel指数。结果治疗前,研究组HAMD-17评分与对照组比较无显著差异(t=0.397,P=0.692);经过治疗,两组患者HAMD-17评分均有所下降,但研究组水平要低于对照组(t=3.401,P=0.001)。治疗前,研究组NIHSS评分与对照组比较无显著差异(t=0.830,P=0.409);经过治疗,两组患者NIHSS评分均有所下降,但研究组水平要低于对照组(t=3.312,P=0.001)。治疗前,研究组Barthel指数与对照组比较无显著差异(t=0.396,P=0.693);经过治疗,两组患者Barthel指数均有所下降,但研究组水平要高于对照组(t=2.876,P=0.005)。结论盐酸舍曲林联合心理治疗可有效缓解脑卒中后抑郁症状,有利于改善患者神经功能以及日常生活活动能力,促进患者恢复。
Objective To investigate the clinical effect of sertraline hydrochloride combined with psychotherapy on patients with post-stroke depression.Methods 106 patients with post-stroke depression received from the Department of Neurology in our hospital between September 2019 and September 2020 were selected as observation objects for retrospective analysis.According to the difference of treatment plan,they were divided into 53 cases in the study group and 53cases in the control group.The control group was given Serin,and the study group was combined with psychotherapy on this basis.The HAMD-17 score,NIHSS score and Barthel index were compared between the two groups.Results Before treatment,the HAMD-17 score of the study group was not significantly different from that of the control group(t=0.830,P=0.409),after treatment,the HAMD-17 score of the two groups of patients decreased,but the level of the study group was lower than that of the control group(t=3.401,P=0.001).Before treatment,the NIHSS score of the study group was not significantly different from that of the control group(t=0.830,P=0.409),after treatment,the NIHSS score of the two groups of patients decreased,but the level of the study group was lower than that of the control group(t=3.312,P=0.001).Before treatment,there was no significant difference between the Barthel index of the study group and the control group(t=0.396,P=0.693),after treatment,the Barthel index of the two groups of patients decreased,but the level of the study group was higher than that of the control group(t=2.876,P=0.005).Conclusion Sertraline hydrochloride combined with psychotherapy can effectively relieve the symptoms of depression after stroke,which is beneficial to improve the patients’neurological function and activities of daily living,and promote the recovery of patients.
作者
马丽华
MA Li-hua(Department of Neurology,Miyun District Hospital,Beijing 101500)
出处
《智慧健康》
2021年第31期130-132,共3页
Smart Healthcare
关键词
盐酸舍曲林
脑卒中
抑郁
神经功能
日常生活能力
Sertraline hydrochloride
Stroke
Depression
Neural function
Activities of daily living
