摘要
目的探索血液高凝状态下慢性阻塞性肺病急性发作合并Ⅱ型呼吸衰竭患者运用那屈肝素钙治疗效果。方法选取湛江市第一中医医院收治的65例(2018年1月-2021年12月)慢性阻塞性肺病急性发作合并Ⅱ型呼吸衰竭患者为研究对象,以数字表法1∶1形式随机分组,32例(对照组)开展常规治疗(抗感染、吸氧、平喘等),33例(观察组)在对照组基础上运用那屈肝素钙治疗,观察两组患者各项临床指标变化、血液流变学指标以及治疗效果。结果治疗前两组患者纤维蛋白原、细胞压积指标无统计学(P>0.05),治疗后观察组患者各项指标低于对照组,统计学意义显著(P<0.05)。治疗前两组患者PaO_(2)、PaCO_(2)、血氧饱和度、凝血酶原时间指标无统计学对比价值(P>0.05),治疗后观察组患者各项指标更优,统计学意义明显(P<0.05)。治疗有效率观察组96.97%、对照组81.25%,数据差异统计学存在(P<0.05)。结论血液高凝状态下的慢性阻塞性肺病急性发作合并Ⅱ型呼吸衰竭患者运用那屈肝素钙治疗效果较为明显,可改善患者临床症状,降低患者并发症发生率,提高生活质量,具有临床推广价值。
Objective To explore the effect of naheparin calcium treatment in patients with chronic obstructive pulmonary disease under blood hypercoagulation.Methods 65 patients(January 2018-December 2021)with COPD were random1:1,32 patients(control group)were carried out routine treatment(antiinfection,oxygen absorption,asthma),33 patients(observation group)were treated with heparin calcium based on the control group to observe changes of clinical indexes,blood rheological index and treatment effect.Results Fiinogen and cell compression were statistical(P>0.05),which were lower than the control group and significant(P<0.05).PaO_(2),PaCO_(2),HO saturation,prothrombin(P>0.05),and significant(P<0.05).96.97%,81.25%,and data difference statistics exist(P<0.05).Conclusion The treatment of heparin in patients with chronic obstructive pulmonary disease in blood coagulation is obvious,which can improve clinical symptoms,reduce the incidence of complications,improve quality of life,and have clinical promotion value.
作者
李云龙
叶思燕
许锦奋
杨良俊
曹映月
刘佳莹
LI Yunlong;YE Siyan;XU Jinfeng;YANG Liangjun;CAO Yingyue;LIU Jiaying(Zhanjiang City First Hospital of Traditional Chinese Medicine,Zhanjiang,Guangdong 524043)
出处
《智慧健康》
2022年第4期106-108,112,共4页
Smart Healthcare
关键词
慢性阻塞性肺病
急性发作
Ⅱ型呼吸衰竭
那屈肝素钙
Chronic obstructive pulmonary disease
Acute attack
Type respiratory failure
That yield heparin calcium
