摘要
目的探讨结核抗体对活动性肺结核患者的诊断价值。方法选取2015年5月-2016年12月在我院治疗的肺结核患者68例作为观察组,另选取同期在我院接受治疗的其他肺部疾病患者55例作为对照组。两组患者均行血清结核抗体检测(结核抗体LgG/LgM检测)和结核菌素试验。观察并比较两种方法的检测结果,及其诊断灵敏度和特异度,判断两种诊断方法对活动性肺结核患者的诊断价值。结果结核抗体LgG/LgM检测菌阳肺结核灵敏度为77.42%,菌阴肺结核灵敏度为59.46%。诊断活动性肺结核中假阳性22例,假阴性7例,总灵敏度为67.64%,特异性为96.36%,准确性为57.35%,阳性预测值为35.29%,阴性预测值为22.06%。结核菌素检测菌阳肺结核灵敏度为50.00%,菌阴肺结核灵敏度为52.94%。诊断活动性肺结核中假阳性18例,假阴性17例,总灵敏度为51.47%,特异性为89.09%,准确性为48.53%,阳性预测值为25.00%,阴性预测值为23.53%。结核抗体LgG/LgM检测的灵敏度和特异度高于结核抗体检测,差异有统计学意义(P<0.05)。结论结核抗体LgG/LgM诊断活动性肺结核更加方便快捷,灵敏度高,特异性强,为检测活动性肺结核提供了科学依据。
Objective To investigate diagnostic value of tuberculosis antibody in patients with active pulmonary tuberculosis.Methods The paper chose 68 patients with pulmonary tuberculosis treated in our hospital from May 2015 to December 2016 as observation group,55 cases with other pulmonary diseases treated in our hospital in the same period were selected as control group.Both groups were treated with serum tuberculosis antibody test(tuberculosis antibody LGG/LGM test)and tuberculin test.Detection results,diagnostic sensitivity and specificity between two methods were observed and compared,diagnostic value between two methods for active pulmonary tuberculosis patients was evaluated.Results Sensitivity of tuberculosis antibody LGG/LGM in detection of bacterial positive pulmonary tuberculosis was 77.42%,sensitivity of bacterial negative pulmonary tuberculosis was 59.46%.Total sensitivity was 67.64%,specificity was 96.36%,accuracy was 57.35%,positive predictive value was 35.29%,negative predictive value was 22.06%.Sensitivity of tuberculin in detection of bacterial positive pulmonary tuberculosis was 50.00%,sensitivity of bacterial negative pulmonary tuberculosis was 52.94%.Total sensitivity was 51.47%,specificity was 89.09%,accuracy was 48.53%,positive predictive value was 25.00%,negative predictive value was 23.53%.Sensitivity and specificity of tuberculosis antibody LGG/LGM was higher than tuberculosis antibody,difference was statistically significant,(P<0.05).Conclusion Tuberculosis antibody can diagnose active pulmonary tuberculosis LGG/LGM more convenient,rapid,sensitive and specific,which provides scientific basis for detection of active pulmonary tuberculosis.
作者
魏君
项倩
WEI Jun;XIANG Qian(Chibi City People's Hospital,Xianning,Hubei,437300)
出处
《智慧健康》
2022年第6期16-18,共3页
Smart Healthcare
关键词
结核抗体
活动性
肺结核
结核菌素
Tuberculosis antibody
Activity
Pulmonary tuberculosis
Tuberculin
作者简介
魏君(1982-),男,湖北赤壁,汉族,本科,学士学位,主治医师,研究方向:肝病,肺结核。
