摘要
目的研讨脑梗死患者采用丁苯肽注射液联合依达拉奉联合治疗的效果。方法选取2019年1月-2021年1月本院脑梗死患者60例,随机分成常规组(30例)、试验组(30例)。常规组实施依达拉奉治疗,试验组在常规治疗的基础上给予丁苯肽进行联合治疗,对比两组脑功能、肢体功能评分、NIHSS评分、生活质量评分、血清S100β含量。结果治疗后,脑功能数值对比,试验组显著更高(P<0.05);肢体功能数值对比,试验组显著高于常规组(P<0.05);入院当天、治疗3d两组NIHSS评分无显著差异(P>0.05),治疗1周后NIHSS评分对比,试验组显著低于常规组(P<0.05)。生活质量各指标对比,试验组显著高于常规组(P<0.05)。治疗前血清S100β含量对比两组无显著差异(P>0.05);治疗后1周、治疗后2周、治疗后3周中血清S100β含量值对比,试验组显著低于常规组(P<0.05)。结论丁苯肽注射液联合依达拉奉用于脑梗死治疗,疗效显著,值得推广。
Objective To investigate effect of combination therapy of butylphenyl peptide injection and edaravone for patients with cerebral infarction.Methods The paper chose 60 patients with cerebral infarction in our hospital from January 2019 to January 2021,and divided them into routine group and experimental group randomly.Routine group was treated with edaravone,while experimental group with combination of butylbenzene peptide on the basis of routine treatment.Brain function,limb function scores,NIHSS scores,life quality scores and serum S100βcontent were compared between two groups.Results After treatment,brain function values in experimental group was significantly higher(P<0.05);limb function values of experimental group were significantly higher than routine group(P<0.05);there was no significant difference in NIHSS scores between two groups on the day of admission and the third day of treatment(P>0.05).After one week of treatment,NIHSS scores in experimental group were significantly lower than routine group(P<0.05).Various indicators of life quality in experimental group were significantly higher than routine group(P<0.05).Before treatment,serum S100βcontent showed no significant difference between two groups(P>0.05);serum S100βcontent at 1 week,2 weeks and 3 weeks after treatment in experimental group was significantly lower than routine group(P<0.05).Conclusion Combination of butylphenyl peptide injection and edaravone flow can achieve significant curative effect in treatment of cerebral infarction,which can be promoted.
作者
张雨
ZHANG Yu(Beidahuang Group Hongxinglong Hospital,Shuangyashan,Heilongjiang 155811)
出处
《智慧健康》
2023年第10期31-34,共4页
Smart Healthcare
关键词
急性脑梗死
依达拉奉
临床疗效
Acute cerebral infarction
Edaravone
Clinical effect
