摘要
目的探究右美托咪定(Dex)在冠状动脉粥样硬化性心脏病(CHD)患者非心脏手术麻醉诱导中的效果。方法选择我院接收的CHD患者120例,均于全身麻醉下接受非心脏手术治疗,按麻醉药物的不同分为对照组和研究组各60例。对照组给予咪达唑仑辅助麻醉诱导,研究组给予Dex辅助麻醉诱导。比较2组麻醉诱导期间血流动力学[心率(HR)、平均动脉压(MAP)]变化情况及不良反应发生情况。结果研究组HR、MAP变化不明显,对照组HR逐渐加快,MAP明显升高,组间、时点间、组间·时点间交互作用差异有统计学意义(P<0.05);研究组呛咳、肌阵挛发生情况优于对照组(P<0.05)。结论Dex能够很好地稳定CHD患者非心脏手术治疗的心率和血压,减少麻醉诱导期间不良反应发生率,提高麻醉及手术安全性。
Objective To investigate the efficacy of dexmedetomidine(Dex)in anesthesia induction for noncardiac surgery in patients with coronary atherosclerotic heart disease(CHD).Methods Totally 120 CHD patients treated in our hospital were included in the study.They were all treated with non-cardiac surgery under general anesthesia.According to the use of different anesthetic drugs,they were divided into control group(n=60)with midazolam assisted anesthesia induction and study group(n=60)with Dex assisted anesthesia induction.The hemodynamic changes and adverse events during anesthesia induction were observed.Results The heart rate(HR)and mean arterial pressure(MAP)of the study group did not change significantly,The HR of the control group gradually accelerated,and the MAP increased significantly.And the difference in the interaction between groups,time points,groups and time points was statistically significant(P<0.05);The occurrence of cough and myoclonus in the study group was better than that in the control group(P<0.05).Conclusion Dex can stabilize the heart rate and blood pressure of CHD patients undergoing non-cardiac surgery,reduce the occurrence of adverse events during anesthesia induction,and improve the safety of anesthesia and surgery.
作者
刘丽丽
LIU Li-li(Department of Anesthesiology,Jiamusi Central Hospital,Jiamusi 154002,China)
出处
《中国误诊学杂志》
CAS
2020年第9期385-387,共3页
Chinese Journal of Misdiagnostics
关键词
冠心病
右美托咪定
非心脏手术
麻醉诱导
coronary disease
dexmedetomidine
noncardiac surgery
anesthesia induction
