摘要
目的探讨阻塞性睡眠呼吸暂停通气综合征(OSAHS)临床特点及其与脑白质损伤的关系。方法选择因打鼾到揭阳市人民医院就诊,并且行睡眠呼吸监测与头颅磁共振检查的患者共81例,根据呼吸紊乱指数(AHI)进行分组,对所有睡眠呼吸监测中的AHI数值与脑小血管病变头颅磁共振标志物中的脑白质病变水平资料进行收集与整理,分析不同程度的OSAHS与脑白质病变之间的联系。结果轻度OSAHS患者的睡眠呼吸质量受到的影响相对较为轻,中重度患者则明显高于轻度患者。高血压、糖尿病、男性以及高龄等均属于中重度OSAHS的危险因素。OSAHS与是否脑白质病变有相关性(P<0.05),AHI越高,脑白质病变的程度越高(P<0.05)。结论严重的OSAHS比程度轻的OSAHS有更大概率发生脑白质病变情况,高血压、糖尿病、男性以及高龄是导致OSAHS的危险因素。
Objective To explore the clinical features of obstructive sleep apnea hypopnea syndrome(OSAHS)and its relationship with brain white matter.Methods A total of 81 patients who performed sleep breathing monitoring and brain magnetic resonance imaging in Jieyang People’s Hospital,grouping according to the respiratory disorder index(AHI).It aim to collect all AHI values in sleep breathing monitoring versus and white matter lesion data in MRI markers of cerebral small vessel disease,and analyze the relationship between different degrees of OSAHS and white matter lesions.Results Compared moderate-severe OSAHS patients,the sleep breathing quality in mild OSAHS patients has relatively lightly affected.Hypertension,diabetes,male as well as advanced age are risk factors for moderate-severe OSAHS.There were a great correlation between OSAHS and white matter lesions(P<0.05),the higher the AHI was,the higher the white matter lesions degree was(P<0.05).Conclusion Severe OSAHS has a greater probability on brain white matter lesions than mild OSAHS.Hypertension,diabetes,male as well as advanced age are the risk factor for OSAHS.
作者
杨丽芝
YANG Li-zhi(Department of Neurology,People's Hospital of Jieyang City,Jieyang522000,China)
出处
《中国误诊学杂志》
CAS
2021年第5期406-407,共2页
Chinese Journal of Misdiagnostics
基金
揭阳市医学科研项目(44011120191092K)
