摘要
目的观察蒲金颗粒辅助治疗小儿痉挛型脑性瘫痪(脑瘫)痰瘀阻窍证的临床疗效。方法选取72例符合痉挛型脑瘫痰瘀阻窍证的患儿,随机分为治疗组和对照组,各36例。对照组给予常规康复治疗,治疗组在对照组治疗方法的基础上加用蒲金颗粒。2组均治疗4周为1个疗程,连续治疗3个疗程后,比较2组治疗前后粗大运动功能、肌张力、智力、言语和中医证候疗效评估。结果2组治疗前粗大运动功能评估(GMFM)评分、智力评分、言语发育评分、双下肢痉挛评分比较,差异均无统计学意义(P>0.05),具有可比性。与同组治疗前比较,2组治疗后GMFM评分、智力评分、言语发育评分均显著升高(P<0.05或P<0.01),且治疗组升高幅度显著大于对照组,而双下肢痉挛评分均显著降低(P<0.05),且治疗组降幅显著大于对照组,差异均有统计学意义(P<0.05)。治疗前,2组下肢关节股角、足背屈角、 角角度和痉挛程度比较,差异无统计学意(P>0.05),具有可比性。治疗后,治疗组的股角、足背屈角、 角的角度评分均显著高于对照组,差异均有统计学意义(P<0.05)。结论在常规康复治疗的基础上加用蒲金颗粒治疗小儿痉挛型脑瘫痰瘀阻窍证,可有效改善脑瘫患儿粗大运动功能、肌张力、智力、言语、中医证候评分。
Objective To observe the effect of Pujin Keli in adjunctive treating of children with spastic cerebral palsy caused by phlegm and blood retention in head.Methods 72 cases of children with spastic cerebral palsy in our hospital were randomly divided into therapy group and control group with 36 cases in each.The control group was given routine rehabilitation treatment,while the therapy group was given Pujin Keli based on the treatment of control group.Both groups were treated for 4 weeks as 1 courses.After 3 courses of treatment,the gross motor function,muscle tone,intelligence,speech and evaluation of TCM syndrome effects in two groups were compared.Results There was no statistically significant difference in the gross motor function measure(GMFM)score,intelligence score,speech development score,and both lower limbs spasticity score between the 2 groups before treatment(P>0.05).Compared with the same group before treatment,the GMFM score,intelligence score,and speech development score were significantly increased after treatment(P<0.05 or P<0.01),besides the increase extent of therapy group was significantly larger than that of the control group,as well as the scores of both lower limbs were significantly lower(P<0.05),and the therapy group was significantly lower than the control group,the difference was statistically significant(P<0.05).Before treatment,there was no statistical significance in lower extremity joint femoral angle,foot dorsal angle,popliteal angle and spasm degree(P>0.05).After treatment,the femoral Angle,dorsal angle and popliteal angle of the therapy group were significantly higher than the control group,and the difference was statistically significant(P<0.05).Conclusion On the basis of routine rehabilitation therapy combined with Pujin Keli in the treatment of children with spastic cerebral palsy caused by phlegm and blood retention in head,in improving the cerebral palsy children with gross motor function,muscle tone,intelligence,language,TCM syndrome that all scores have good effect.
作者
马丙祥
张建奎
陈恬恬
郑宏
MA Bingxiang;ZHANG Jiankui;CHEN Tiantian;ZHENG Hong(Department of Pediatrics,the First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou,Henan,450000,China)
出处
《中医儿科杂志》
2018年第3期26-30,共5页
Journal of Pediatrics of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(81473727)
河南省重点中医学科(专科)学术带头人培养项目专项课题(2013ZY03010)。
关键词
小儿
脑性瘫痪
痉挛型
痰瘀阻窍
蒲金颗粒
临床观察
children
cerebral palsy
spasm type
obstruction of phlegm and stasis
Pujin Keli
clinical observation
作者简介
马丙祥(1963-),男,教授,主任医师,医学博士,主要从事中医药防治小儿神经系统疾病的研究工作。
