摘要
目的观察热毒宁注射液辅助治疗儿童支原体肺炎的临床疗效及安全性。方法选取2015年6月至2017年5月我院儿科收治的64例支原体肺炎患儿,随机分为治疗组和对照组,各32例。2组入院后均给予退热、止咳化痰等常规及对症支持治疗,对照组在此基础上静脉滴注阿奇霉素,治疗组在对照组治疗方法的基础上静脉滴注热毒宁注射液,2组均以5 d为1个疗程,连续治疗2个疗程后统计疗效及不良反应发生情况。结果治疗组总有效率为93.75%,对照组为71.88%,2组比较,差异有统计学意义(P<0.05);治疗组湿 音、咳嗽、咳痰、喘促、发热消失时间均显著短于对照组,经统计学分析,差异有统计学意义(P<0.05);治疗组不良反应总发生率为9.36%,对照组为31.25%,2组比较,差异有统计学意义(P<0.05)。结论热毒宁注射热辅助治疗儿童支原体肺炎疗效确切,能快速缓解患儿的临床症状、体征,降低不良反应发生率,可在临床中推广应用。
Objective To observe the clinical efficacy and safety of mycoplasma pneumonia in children treated with Reduning Injection as an adjuvant therapy.Methods 64 cases of children with mycoplasma pneumonia in our hospital from June 2015 to May 2017 were selected and divided randomly into therapy group and control group with32 cases in each.The 2 groups were given conventional and symptomatic supportive treatment after hospitalization,such as defervescence,curing cough and reducing phlegm.In the control group,azithromycin was intravenously dripped on the basis of the original treatment,while the therapy group was treated with Reduning by intravenous injection on the basis of the control group.All patients were treated with 5 days for 1 course.After 2 courses of treatment,the efficacy and adverse reactions were statistically analyzed.Results The total effective rate in therapy group was 93.75%,much higher than 71.88%of control group,differences had significance(P<0.05);the moist rales,cough,expectoration,panting and fever disappeared time in the therapy group were all significantly shorter than that in the control group,and the difference was statistically significant(P<0.05);the total incidence of adverse reactions in the therapy group was 9.36%,which was 31.25%in the control group,the difference between the 2 groups was statistically significant(P<0.05).Conclusion Reduning Injection as an adjuvant therapy can treat children with mycoplasma pneumonia effectively.It can quickly relieve the clinical symptoms and signs of children,and reduce the incidence of adverse reactions,which can be widely applied in clinical practice.
作者
施霞静
SHI Xiajing(Department of Pediatrics,Xiaogang Hospital of Beilun District in Ningbo City,Ningbo,Hangzhou,315801,China)
出处
《中医儿科杂志》
2018年第3期33-36,共4页
Journal of Pediatrics of Traditional Chinese Medicine
关键词
支原体肺炎
儿童
热毒宁注射液
安全性
临床观察
mycoplasma pneumonia
children
Reduning Injection
safety
clinical observation
作者简介
施霞静(1980-),女,主治医师,医学学士,主要从事儿科临床诊疗工作。
