摘要
目的:分析多囊卵巢综合征(Polycystic Ovary Syndrome,PCOS)患者卵巢大小及促黄体生成素(Luteinizing Hormone,LH)、卵泡刺激素(Follicle Stimulating Hormone,FSH)水平是否与中医体质相关,为中医“治未病”,临床辨证、辨病、辨体相结合防治PCOS提供参考。方法:纳入2019年就诊于成都中医药大学附属医院妇科门诊确诊为PCOS的患者79例。通过问卷调查,依据《中医体质分类与判定》判定中医体质类型,测定超声形态学下卵巢体积参数以及LH、FSH、LH/FSH指标水平,观察中医体质分型分布情况。结果:(1)79例PCOS患者中医体质分布:气郁质(25.32%)、痰湿质(18.99%)、湿热质(17.72%)、阳虚质(15.19%)、血瘀质(13.92%)、气虚质(8.86%)。(2)其中湿热质的平均卵巢体积最大,痰湿质次之,阳虚质平均卵巢体积最小。(3)研究中阳虚质的LH、LH/FSH值均高于其他5种体质,气虚质的FSH值略高于其他5种体质。湿热质的FSH值与血瘀质比较,湿热质的LH值与阳虚质比较,痰湿质的LH值与阳虚质比较,湿热质的LH/FSH与气郁质比较,差异均有统计学意义(P<0.05)。结论:(1)本研究PCOS患者中,体质以气郁质、痰湿质、湿热质、阳虚质多见。(2)湿热质平均卵巢体积最大,其次为痰湿质,阳虚质最小。(3)阳虚质的LH、LH/FSH值明显高于其他体质,气虚质的FSH较其他体质略高。(4)PCOS患者卵巢大小及LH、FSH水平与中医体质之间存在关系。通过经阴道超声检查了解卵巢体积,结合LH、FSH指标水平评估患者体质类型,同时与辨证、辨病相结合,对于PCOS疾病的防治有一定的辅助性作用。
Objective:To analyze whether ovarian size and luteinizing hormone(LH)and follicle stimulating hormone(FSH)level in women with polycystic ovary syndrome(PCOS)is related to TCM constitution,and to provide reference for the treatment and prevention of PCOS by combining clinical syndrome differentiation,disease differentiation and body discrimination.Methods:A total of 79 women diagnosed with PCOS in the gynecological clinic of Affiliated Hospital of Chengdu University of Traditional Chinese Medicine in 2019 were included.Through questionnaire survey,the types of TCM constitution were determined according to the Classification and Judgment of TCM Constitution,and the ovarian volume parameters and the index levels of LH,FSH and LH/FSH under ultrasonic morphology were measured to observe the distribution of TCM constitution types.Results:①The distribution of TCM constitution of 79 female PCOS:Qi(气)stagnation(25.32%),phlegm-dampness(18.99%),damp-heat(17.72%),Yang(阳)deficiency(15.19%),blood stasis(13.92%),Qi deficiency(8.86%).②The average ovarian volume of the damp-heat was the largest,which was followed by the phlegm-dampness,and the average ovarian volume of Yang deficiency was the smallest.③In the study,the LH and LH/FSH values of Yang deficiency were higher than those of the other 5 constitutions,and the FSH values of Qi deficiency were slightly higher than those of the other 5 constitutions.There were statistically significant differences between the FSH value of damp-heat and blood-stasis,the LH value of damp-heat and yang deficiency,the LH value of phlegm-dampness and Yang dficiency,and the LH/FSH of damp-heat and Qi stagnation(P<0.05).Conclusion:①In this study,Qi stagnation,phlegm-dampness,damp-heat and Yang deficiency are the most common constitutions in women with pcos.②The average ovarian volume is the highest in damp-heat,followed by phlegm-dampness and Yang deficiency.③The LH and LH/FSH values of Yang deficiency are significantly higher than those of other constitutions,and the FSH values of Qi deficiency are slightly higher than those of other constitutions.④There is a relationship between ovarian size,LH and FSH levels and TCM constitution in PCOS women.Utilizing transvaginal ultrasonography to understand ovarian volume,combined with LH and FSH index levels to assess the physical type of patients,and combined with syndrome differentiation and disease differentiation,has a certain auxiliary effect for the prevention of PCOS disease.
出处
《中医临床研究》
2023年第3期144-148,共5页
Clinical Journal Of Chinese Medicine
基金
国家自然科学基金委员会资助项目(3252018037)
四川省应用基础研究项目(319020031)
关键词
多囊卵巢综合征
中医体质
卵巢体积
促黄体生成素
卵泡刺激素
Polycystic ovary syndrome
TCM constitution identification
Ovarian volume
Luteinizing hormone
Follicle stimulating hormone
作者简介
通讯作者:王雯雯(1997―),女,硕士研究生,主要研究方向为中医药防治不孕症的临床研究。
