摘要
This work is focused on developing zinc-doped hydroxyapatite-zeolite(Zn HA-Zeo)and polycaprolactone(PCL)composite coatings on magnesium(Mg)substrate to improve the corrosion resistance and antimicrobial properties.Dip-coating technique was used to coat Zn HA-Zeo/PCL on the Mg substrate at room temperature.The samples were subjected to field emission scanning electron microscopy(FESEM),X-ray diffraction(XRD),Fourier transform infrared(FTIR),energy dispersive X-ray spectroscopy(EDX)and antimicrobial potential.Results demonstrated that composite coatings consist of HA,scholzite,zeolite,and PCL phases.EDX spectra indicated the presence of calcium(Ca),silicon(Si),aluminum(Al),zinc(Zn),phosphorus(P)and oxygen(O).The composite surface appeared in spherical-like microstructure on coating with thickness ranging 226-260μm.Zinc-doped HA-Zeo composite coating had a high corrosion resistance and provided sufficient protection to the Mg surface against galvanic corrosion.Doped Zn HA-Zeo coating samples exhibited superior disc inhibition by confirming antimicrobial activity against the E.coli as compared to HA-Zeo sample.Altogether these results showed that the Zn HA-Zeo coatings not only improved the corrosion resistance,but also enhanced the antimicrobial property and hence they can be used as suitable candidates for implant applications.
开发掺锌羟基磷灰石-沸石(Zn HA-Zeo)和聚己内酯(PCL)复合涂层,以提高镁基体的耐腐蚀性能和抗菌性能。采用浸涂技术在室温下将Zn HA-Zeo/PCL涂覆在镁基体上,对样品进行场发射扫描电子显微镜(FESEM)、X射线衍射(XRD)、傅里叶变换红外光谱(FTIR)、能量色散X射线光谱(EDX)和抗菌电位测试。结果表明,复合涂层由羟基磷灰石(HA)、磷钙锌石(scholzite)、沸石和PCL相组成。EDX谱显示钙(Ca)、硅(Si)、铝(Al)、锌(Zn)、磷(P)和氧(O)元素的存在。复合涂层表面的显微形貌为球形,厚度为226~260μm。掺锌HA-Zeo复合涂层具有较高的耐蚀性,对镁基体表面提供足够的保护,使其不被电流腐蚀。与未掺杂的涂层相比,掺锌HA-Zeo涂层对大肠杆菌具有更好的抗菌活性。综合结果表明,Zn HA-Zeo涂层不仅具有良好的耐腐蚀性能,而且具有良好的抗菌性能,可作为种植体应用的理想材料。
基金
supported by University of Engineering and Technology,Lahore,faculty under research project#ORIC/102-ASRB/1288 and UTM,FRGS grant#R.J130000.7845.4F768.
作者简介
Corresponding author:Nida IQBAL,Tel:+92-3434172495,E-mail:nidaiqbal@uet.edu.pk
