摘要
目的:探讨特发性黄斑前膜手术治疗效果及安全性。方法:特发性黄斑前膜21眼行玻璃体手术,术后1,3,6及12mo,进行视力、光学相干断层成像(op-ticalcoherencetomography,OCT)、多焦视网膜电流图(multifocalelectroretinogram,MERG)检查,应用SPSS11.5软件对结果进行统计学分析。结果:手术后12mo视力改善2行以上90%(19/21),视物变形改善81%(17/21),与术前比较有显著性差异(P<0.05);OCT显示前膜消失,手术前视网膜平均厚度496.8±93.0μm,术后12mo平均厚度176.1±28.0μm,与术前比较有显著性差异(P<0.05);术前MERG地形图可见中心峰下降,一级反应1、2环P1波反应密度明显降低,术后1￣12moMERG中央峰逐渐恢复;1、2环P1波反应密度明显升高,与术前比较有显著性差异(P<0.05)。结论:玻璃体手术治疗特发性黄斑前膜疗效可靠,OCT及MERG可以较好地客观评价视功能的恢复。
AIM： To evaluate the safety and efficacy of idiopathic macular membrane surgery. METHODS： 21 eyes of 21 patients with idiopathic macular membrane underwent vitrectomy. Visual acuity, optical coherence tomography （OCT） and multifocal electroretinogram （HERG） were examined preoperatively and 1,3,6, and 12mo postoperatively. The results were analyzed statistically by SPSSll.5. RESULTS： （ 1）12mo after the surgery, patients whose visual acuity elevation was more than 2 line accounted for 90% （19/21）, patients whose visual distortion was improved accounted for about 81% （17/21） （P〈0.05）; （2） OCT showed all the HEH disappeared. The average retina thickness was 496.76± 93mm preoperatively and 176.1± 28.0mm postoperatively, the difference was significant （P〈0.05）; （3） The MERG central peaks, the response densities of wave P1 of ring 1 and ring 2 were low before the operation, while obviously increased after the operation （P〈0.05）. CONCLUSION： The efficiency of vitreous surgery on treatment of idiopathic macular membrane is obvious, and can be evaluated by the visual acuity, OCT and MERG.
出处
《国际眼科杂志》
CAS
2006年第1期132-134,共3页
International Eye Science
作者简介
通讯作者：王丽丽，女，毕业于西安医学院，主任医师，业务副院长，西安市眼底病研究所所长，研究方向：玻璃体视网膜病。wanglili722@sohu．com
