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Can sacubitril/valsartan become the promising drug to delay the progression of chronic kidney disease?
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作者 Yang CHEN Lu-Ying GUO +4 位作者 Ling-Fei ZHAO Yan-Hong MA Xue-Ling ZHU Ying XU Jiang-Hua CHEN 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2020年第12期782-786,共5页
1 Introduction Chronic kidney disease(CKD)often coexists with or is a complication of cardiovascular disease.Previous studies have shown that CKD increases the risk of cardiovascular death and all-cause death and was ... 1 Introduction Chronic kidney disease(CKD)often coexists with or is a complication of cardiovascular disease.Previous studies have shown that CKD increases the risk of cardiovascular death and all-cause death and was considered to be a risk equivalent of coronary heart disease.[1,2]Adjusted for confounders,decreased glomerular filtration rate(GFR)and increased albuminuria are both independent risk factors for cardiovascular events.[3,4]The risk for cardiovascular death linearly increases with the decline of GFR in a certain range(<70 mL/min per 1.73 m^2)and the increase of albuminuria without a threshold effect[3]. 展开更多
关键词 Cardiovascular disease Chronic kidney disease Kidney function Sacubitril/valsartan
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