Dear Editor,Most battlefield casualties occur prior to the arrival of medical facilities.Uncontrollable hemorrhage accounts for more than 90%of those potentially survivable battlefield casualties[1].In both military a...Dear Editor,Most battlefield casualties occur prior to the arrival of medical facilities.Uncontrollable hemorrhage accounts for more than 90%of those potentially survivable battlefield casualties[1].In both military and civilian conditions,non-compressible torso hemorrhage always caused rapid exsanguination and high mortality rates before definitive treatment[2].More than half of the deaths due to non-compressible torso hemorrhage occur before hospital care can be provided[2].Therefore,early and rapid pre-hospital hemorrhage control is essential to reduce mortality.展开更多
Ammonium level in body fluids serves as one of the critical biomarkers for healthcare,especially those relative to liver diseases.The continuous and real-time monitoring in both invasive and noninvasive manners is hig...Ammonium level in body fluids serves as one of the critical biomarkers for healthcare,especially those relative to liver diseases.The continuous and real-time monitoring in both invasive and noninvasive manners is highly desired,while the ammonium concentrations vary largely in different body fluids.Besides,the sensing reliability based on ion-selective biosensors can be significantly interfered by potassium ions.To tackle these challenges,a flexible and biocompatible sensing patch for wireless ammonium level sensing was reported with an ultrawide linear range for universal body fluids including blood,tears,saliva,sweat and urine.The as-prepared biocompatible sensors deliver a reliable sensitivity of 58.7 mV decade-1 in the range of 1-100 mM and a desirable selectivity coefficient of 0.11 in the interference of potassium ions,attributed to the cross-calibration within the sensors array.The sensor’s biocompatibility was validated by the cell growth on the sensor surface(>80%),hemolysis rates(<5%),negligible cellular inflammatory responses and weight changes of the mice with implanted sensors.Such biocompatible sensors with ultrawide linear range and desirable selectivity open up new possibility of highly compatible biomarker analysis via different body fluids in versatile approaches.展开更多
In China,there are 544,000 sudden deaths each year.Cardiac arrest is one of the most common causes of sudden death,and 70%of cardiac arrests occur outside the hospital.[1,2]However,fewer than 1%of bystanders at cardia...In China,there are 544,000 sudden deaths each year.Cardiac arrest is one of the most common causes of sudden death,and 70%of cardiac arrests occur outside the hospital.[1,2]However,fewer than 1%of bystanders at cardiac arrest deaths in China are well-trained and capable of administering first aid.[3]Therefore,it is urgent to popularize first-aid knowledge in the Chinese population.展开更多
Dear editor,The incidence of renal infarction in patients admitted to the emergency department(ED) is approximately 0.004%.[1]Among patients with renal infarction, bilateral renal involvement has been reported in 28.6...Dear editor,The incidence of renal infarction in patients admitted to the emergency department(ED) is approximately 0.004%.[1]Among patients with renal infarction, bilateral renal involvement has been reported in 28.6% of patients.[2]However, there are very few cases of bilateral renal infarction after a traumatic injury.展开更多
文摘Dear Editor,Most battlefield casualties occur prior to the arrival of medical facilities.Uncontrollable hemorrhage accounts for more than 90%of those potentially survivable battlefield casualties[1].In both military and civilian conditions,non-compressible torso hemorrhage always caused rapid exsanguination and high mortality rates before definitive treatment[2].More than half of the deaths due to non-compressible torso hemorrhage occur before hospital care can be provided[2].Therefore,early and rapid pre-hospital hemorrhage control is essential to reduce mortality.
基金supported by the National Natural Science Foundation of China(62201243)Natural Science Foundation of Guangdong Province(2022A1515011928)+2 种基金Shenzhen Science and Technology Program(Grant No.RCYX20231211090432060,JSGGZD20220822095600001)Postgraduate Scientific Research Innovation Project of Hunan Province(CX20231306)the technical support from the Southern University of Science and Technology Core Research Facilities(SUSTech CRF)。
文摘Ammonium level in body fluids serves as one of the critical biomarkers for healthcare,especially those relative to liver diseases.The continuous and real-time monitoring in both invasive and noninvasive manners is highly desired,while the ammonium concentrations vary largely in different body fluids.Besides,the sensing reliability based on ion-selective biosensors can be significantly interfered by potassium ions.To tackle these challenges,a flexible and biocompatible sensing patch for wireless ammonium level sensing was reported with an ultrawide linear range for universal body fluids including blood,tears,saliva,sweat and urine.The as-prepared biocompatible sensors deliver a reliable sensitivity of 58.7 mV decade-1 in the range of 1-100 mM and a desirable selectivity coefficient of 0.11 in the interference of potassium ions,attributed to the cross-calibration within the sensors array.The sensor’s biocompatibility was validated by the cell growth on the sensor surface(>80%),hemolysis rates(<5%),negligible cellular inflammatory responses and weight changes of the mice with implanted sensors.Such biocompatible sensors with ultrawide linear range and desirable selectivity open up new possibility of highly compatible biomarker analysis via different body fluids in versatile approaches.
基金funded by the Key Project of Hunan Provincial Science and Technology Innovation(2020SK1011,2020SK1010)。
文摘In China,there are 544,000 sudden deaths each year.Cardiac arrest is one of the most common causes of sudden death,and 70%of cardiac arrests occur outside the hospital.[1,2]However,fewer than 1%of bystanders at cardiac arrest deaths in China are well-trained and capable of administering first aid.[3]Therefore,it is urgent to popularize first-aid knowledge in the Chinese population.
文摘Dear editor,The incidence of renal infarction in patients admitted to the emergency department(ED) is approximately 0.004%.[1]Among patients with renal infarction, bilateral renal involvement has been reported in 28.6% of patients.[2]However, there are very few cases of bilateral renal infarction after a traumatic injury.
