Objective Our aim is to construct an indicator system for the graduate dissertation quality evaluation,based on Fuzzy Analytical Hierarchy Process(FAHP).Methods First,we reviewed the related literature to identify and...Objective Our aim is to construct an indicator system for the graduate dissertation quality evaluation,based on Fuzzy Analytical Hierarchy Process(FAHP).Methods First,we reviewed the related literature to identify and select possible factors.Second,we developed an analytic hierarchy process framework.展开更多
Objective To elucidate the transformation of energy metabolism patterns in the process of myocardial remodeling induced by volumeoverload and to explore a novel intervention target for the prevention,delay or even rev...Objective To elucidate the transformation of energy metabolism patterns in the process of myocardial remodeling induced by volumeoverload and to explore a novel intervention target for the prevention,delay or even reversal of structural heart dysfunction.Methods Thirty C57/BL6 mice,20-30 g,half male and half female,were randomly divided into model group(n=15)and sham operation group(n=15).Each group was divided into subacute phase(2 weeks after surgery,n=5),cardiac functional compensation phase(5 weeks after surgery,n=5)and decompensation phase(15 weeks after surgery,n=5).展开更多
Objective Mitochondria serve as energy generators, and its energy metabolism disorder is a key factor in myocardial remodeling. The purpose of this study was to investigate the role of PINK1-Mfn2-Parkinmediated mitoch...Objective Mitochondria serve as energy generators, and its energy metabolism disorder is a key factor in myocardial remodeling. The purpose of this study was to investigate the role of PINK1-Mfn2-Parkinmediated mitochondrial autophagy in the development and progression of myocardial remodeling, which is important for mitochondrial quality control and maintenance of cellular energy metabolism homeostasis.展开更多
文摘Objective Our aim is to construct an indicator system for the graduate dissertation quality evaluation,based on Fuzzy Analytical Hierarchy Process(FAHP).Methods First,we reviewed the related literature to identify and select possible factors.Second,we developed an analytic hierarchy process framework.
文摘Objective To elucidate the transformation of energy metabolism patterns in the process of myocardial remodeling induced by volumeoverload and to explore a novel intervention target for the prevention,delay or even reversal of structural heart dysfunction.Methods Thirty C57/BL6 mice,20-30 g,half male and half female,were randomly divided into model group(n=15)and sham operation group(n=15).Each group was divided into subacute phase(2 weeks after surgery,n=5),cardiac functional compensation phase(5 weeks after surgery,n=5)and decompensation phase(15 weeks after surgery,n=5).
文摘Objective Mitochondria serve as energy generators, and its energy metabolism disorder is a key factor in myocardial remodeling. The purpose of this study was to investigate the role of PINK1-Mfn2-Parkinmediated mitochondrial autophagy in the development and progression of myocardial remodeling, which is important for mitochondrial quality control and maintenance of cellular energy metabolism homeostasis.