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EFFICACY OF PROSTAGLANDINS IN THE EYE
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作者 R.K.Parrish 《国际眼科杂志》 CAS 2003年第1期120-120,共1页
The prostaglandin derivatives have been approved for marketing for the last 6 years and have been shown to be more effective in lowering IOP than most previously available drugs. The distinguishing characteristics of ... The prostaglandin derivatives have been approved for marketing for the last 6 years and have been shown to be more effective in lowering IOP than most previously available drugs. The distinguishing characteristics of the prostaglandin derivatives include a unique mechanism of action, once-daily dosing and the lack of systemic side effects. The prostaglandin derivatives that 展开更多
关键词 前列腺素衍生物 眼压 药效 作用机制 药物副作用 临床试验
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TITANIUM SAPHIRE LASER TRABECULO- PLASTY IN CATS
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作者 V.Fernadez J.Stoiber +5 位作者 P.Lamar E.Hernandez F.Manns N.Salas F.Fantes J.M.Parel 《国际眼科杂志》 CAS 2003年第1期91-91,共1页
Purpose: To assess the safety of a novel Titanium Sapphire laser for trabeculoplasty in an animal model. Methods: The left eye of 6 healthy cats was treated over 180 degrees, while the right eye was used as a control.... Purpose: To assess the safety of a novel Titanium Sapphire laser for trabeculoplasty in an animal model. Methods: The left eye of 6 healthy cats was treated over 180 degrees, while the right eye was used as a control. A Ti:A1203 laser (790nm, four to five 200ns pulses, 7 microseconds pulse train, 200um spot, SOLX, Boston, MA) producing energies of 8 to 84mJ was used. 展开更多
关键词 动物模型 激光小梁成形术 安全性 SEM 眼内结构
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MAKING SENSE OF CLINICAL TRIALS IN GLAUCOMA - GLAUCOMA LASER TRIAL (GLT)
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作者 R.Parrish 《国际眼科杂志》 CAS 2003年第1期116-116,共1页
The Glaucoma Laser Trial (GLT), the first randomized controlled clinical trial of glaucoma treatment, substantially influenced subsequent ophthalmic research. Principles of randomization, objective determination of gl... The Glaucoma Laser Trial (GLT), the first randomized controlled clinical trial of glaucoma treatment, substantially influenced subsequent ophthalmic research. Principles of randomization, objective determination of glaucomatous progression with standard definitions of visual field damage, stepped treatment regi- 展开更多
关键词 青光眼 激光疗法 GLT 临床试验 随访
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NEW INSIGHT INTO MECHANISMS OF AQUEOUS OUTFLOW DEFICIENCY: ROLE OF THE STRESS RESPONSE
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作者 M.E.Fini K.A.Erickson +5 位作者 E.L.Ginsberg P.F.Olson N.Wang K.R.Wollen-berg X.Zhang J.S.Schuman 《国际眼科杂志》 CAS 2003年第1期102-102,共1页
The glaucomas are a group of optic neuropathies comprising the leading cause of irreversible blindness worldwide. Elevated intraocular pressure due to a reduction in normal aqueous outflow is a major causal risk facto... The glaucomas are a group of optic neuropathies comprising the leading cause of irreversible blindness worldwide. Elevated intraocular pressure due to a reduction in normal aqueous outflow is a major causal risk factor. We recently reported that En-dothelial Leukocyte Adhesion Molecule-1 (ELAM-1), the earliest marker for the atherosclerotic plaque in the vasculature. 展开更多
关键词 青光眼 房水外流不足 机制 应激反应 ELAM-1 IL-1
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