Methoxybenzaldehyde is prepared from the addition-hydrolysis reaction of p-CH 3OC 6H 4MgBr with 1,3-disubstituted benzimidazolium salt. The reaction mechanism is discussed. 1,3-Dialkyl has little influence on the yield.
1,3-dimethyl-2-substituted benzimidazolium salt can be easily prepared from carboxylic acid,o-phenylenediamine and methyl iodide via cyclization and quarternarization.It reacts with sodium hydrogen telluride in ethano...1,3-dimethyl-2-substituted benzimidazolium salt can be easily prepared from carboxylic acid,o-phenylenediamine and methyl iodide via cyclization and quarternarization.It reacts with sodium hydrogen telluride in ethanol solution to produce 1,3-dimethyl-2-substituted benzimidazolidine.The reaction mechanism is discussed.Two benzimidazolidines are characterized by means of elemental analysis,IR and 1H NMR.Aldehydes are synthesized by hydrolysis reaction of the benzimidazolidines.Then,a novel synthetic method for aldehydes from the corresponding carboxylic acids via reduction-hydrolysis reaction of benzimidazolium salts is presented.The effect of 2-substituting group of benzimidazolium salts on the yield is discussed.展开更多
文摘Methoxybenzaldehyde is prepared from the addition-hydrolysis reaction of p-CH 3OC 6H 4MgBr with 1,3-disubstituted benzimidazolium salt. The reaction mechanism is discussed. 1,3-Dialkyl has little influence on the yield.
文摘1,3-dimethyl-2-substituted benzimidazolium salt can be easily prepared from carboxylic acid,o-phenylenediamine and methyl iodide via cyclization and quarternarization.It reacts with sodium hydrogen telluride in ethanol solution to produce 1,3-dimethyl-2-substituted benzimidazolidine.The reaction mechanism is discussed.Two benzimidazolidines are characterized by means of elemental analysis,IR and 1H NMR.Aldehydes are synthesized by hydrolysis reaction of the benzimidazolidines.Then,a novel synthetic method for aldehydes from the corresponding carboxylic acids via reduction-hydrolysis reaction of benzimidazolium salts is presented.The effect of 2-substituting group of benzimidazolium salts on the yield is discussed.
