During the past few years, atomic force microscope (AFM) is becoming a powerful tool in life science research. With their high-resolution and capability to image under aqueous solution, AFM is applied to investigate t...During the past few years, atomic force microscope (AFM) is becoming a powerful tool in life science research. With their high-resolution and capability to image under aqueous solution, AFM is applied to investigate the structure of biomolecules and biological process in real time. From visualization of DNA and IgG to DNA transcription, the advances in sample preparation methods have made these events come true. In addition, AFM can be used in molecular recognition. This article illustrates these major achievements of AFM in biological studies.展开更多
基金国家自然科学基金资助 (No .3 9670 690 ) 广东省自然科学基金资助 (No .960 196)
文摘During the past few years, atomic force microscope (AFM) is becoming a powerful tool in life science research. With their high-resolution and capability to image under aqueous solution, AFM is applied to investigate the structure of biomolecules and biological process in real time. From visualization of DNA and IgG to DNA transcription, the advances in sample preparation methods have made these events come true. In addition, AFM can be used in molecular recognition. This article illustrates these major achievements of AFM in biological studies.
