抑郁症是一种高患病率、高致残率以及高自杀率的严重精神性疾患,属于情感性精神障碍。中药及天然药物是抗抑郁先导化合物和新药发现的重要来源。本文系统查阅Springer LINK、Sci-Hub、Web of Science等英文数据库以及CNKI学术文献总库,...抑郁症是一种高患病率、高致残率以及高自杀率的严重精神性疾患,属于情感性精神障碍。中药及天然药物是抗抑郁先导化合物和新药发现的重要来源。本文系统查阅Springer LINK、Sci-Hub、Web of Science等英文数据库以及CNKI学术文献总库,发现1987年至2017年共有157篇与中药及天然药物化学成分抗抑郁作用研究相关的文献,其中国外140篇,国内17篇。然后,从结构类型、生物活性、作用机制等方面综述其研究进展,为抗抑郁新药发现和药物设计提供依据。展开更多
This study explores the controllable synthesis of CuAlO_(2) using copper hydroxide and pseudo-boehmite powders as raw materials via a simple solid-phase ball milling method,along with its catalytic performance investi...This study explores the controllable synthesis of CuAlO_(2) using copper hydroxide and pseudo-boehmite powders as raw materials via a simple solid-phase ball milling method,along with its catalytic performance investigation in methanol steam reforming(MSR).Various catalysts were prepared under different conditions,such as calcination temperature,calcination atmosphere,and heating rate.Characterization techniques including BET,XRD,XPS,SEM and H2-TPR were employed to analyze the samples.The results revealed significant effects of calcination temperature on the phase compositions,specific surface area,reduction performance,and surface properties of the CA-T catalysts.Based on the findings,a synthesis route of CuAlO_(2) via the solid-phase method was proposed,highlighting the importance of high calcination temperature,nitrogen atmosphere,and low heating rate for CuAlO_(2) formation.Catalytic evaluation data demonstrated that CuAlO_(2) could catalyze MSR without pre-reduction,with the catalytic performance of CA-T catalysts being notably influenced by calcination temperature.Among the prepared catalysts,the CA-1100 catalyst exhibited the highest catalytic activity and stability.The findings of this study might be useful for the further study of the catalytic material for sustained release catalysis,including the synthesis of catalytic materials and the regulation of sustained release catalytic performance.展开更多
文摘抑郁症是一种高患病率、高致残率以及高自杀率的严重精神性疾患,属于情感性精神障碍。中药及天然药物是抗抑郁先导化合物和新药发现的重要来源。本文系统查阅Springer LINK、Sci-Hub、Web of Science等英文数据库以及CNKI学术文献总库,发现1987年至2017年共有157篇与中药及天然药物化学成分抗抑郁作用研究相关的文献,其中国外140篇,国内17篇。然后,从结构类型、生物活性、作用机制等方面综述其研究进展,为抗抑郁新药发现和药物设计提供依据。
基金supported by the Scientific Research Foundation for High-level Talents of Anhui University of Science and Technology(2023yjrc51)the National Natural Science Foundation of China(22172184)+2 种基金the Foundation of State Key Laboratory of Coal Conversion(J24-25-603)the Fundamental Research Project of ICC-CAS(SCJC-DT-2023-01)Weiqiao-UCAS Special Projects on Low-Carbon Technology Development(GYY-DTFZ-2022-015)。
文摘This study explores the controllable synthesis of CuAlO_(2) using copper hydroxide and pseudo-boehmite powders as raw materials via a simple solid-phase ball milling method,along with its catalytic performance investigation in methanol steam reforming(MSR).Various catalysts were prepared under different conditions,such as calcination temperature,calcination atmosphere,and heating rate.Characterization techniques including BET,XRD,XPS,SEM and H2-TPR were employed to analyze the samples.The results revealed significant effects of calcination temperature on the phase compositions,specific surface area,reduction performance,and surface properties of the CA-T catalysts.Based on the findings,a synthesis route of CuAlO_(2) via the solid-phase method was proposed,highlighting the importance of high calcination temperature,nitrogen atmosphere,and low heating rate for CuAlO_(2) formation.Catalytic evaluation data demonstrated that CuAlO_(2) could catalyze MSR without pre-reduction,with the catalytic performance of CA-T catalysts being notably influenced by calcination temperature.Among the prepared catalysts,the CA-1100 catalyst exhibited the highest catalytic activity and stability.The findings of this study might be useful for the further study of the catalytic material for sustained release catalysis,including the synthesis of catalytic materials and the regulation of sustained release catalytic performance.
