A Schiff base derived from 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone(PMBP) with p-aminodimethyl aniline and its complexes with Cu(Ⅱ), Co(Ⅱ), Ni(Ⅱ) and Zn(Ⅱ) have been prepared and characterized by elemental analysi...A Schiff base derived from 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone(PMBP) with p-aminodimethyl aniline and its complexes with Cu(Ⅱ), Co(Ⅱ), Ni(Ⅱ) and Zn(Ⅱ) have been prepared and characterized by elemental analysis, IR, UV and 1H NMR techniques. The ligand and the complexes particurally the Co(Ⅱ) complex have antibacterial activities against Escherichia cocli and Staphylococcus aureus.展开更多
Four hydroxamic acid derivaties were prepared by reaction of hydroxylamine hydrochloride with dimethylphthalate, dimethylisophthalate, dimethylterephthalate and dimethylsebacate respectively and characterized by IR an...Four hydroxamic acid derivaties were prepared by reaction of hydroxylamine hydrochloride with dimethylphthalate, dimethylisophthalate, dimethylterephthalate and dimethylsebacate respectively and characterized by IR and elemental analysis. The antibacterial activities to Escherichia coli and Staphylococcus aureus of phthaloyl, isophthaloyl, terephthaloyl and sebacoyl hydroxamic acids have been determined using paper disc method. The result indicates that their antibacterial activities to Escherichia coli are better than that to Staphylococcus aureus and among them the sebacoyl hydroxamic acid is the best one. No linear correlation was observed between the antibacterial activities and the concentration of the compounds, each has its optimum antibacterial concentration.展开更多
The crystal structure and molecular structures of the title compound were determined using Xray analysis.The crystal belongs to monoclinic system with the space group P21/c,C21H20N4O2,with Mr=358...The crystal structure and molecular structures of the title compound were determined using Xray analysis.The crystal belongs to monoclinic system with the space group P21/c,C21H20N4O2,with Mr=35839,a=12845(3),b=19334(4),c=073112(5)nm,β=9443(3)°,V=18103(4)nm3,Z=4,DC=132Mg·m-3,μ=0088mm-1,and F(000)=752.The final discrepancy factor R1=01508,and S=0942.The result showed that the dihedral angles between the two pyrazolinone rings and phenyl rings were 1267 and 798°,which indicated that these two planes roughly coplanar to each other forming a big conjugate system.展开更多
文摘A Schiff base derived from 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone(PMBP) with p-aminodimethyl aniline and its complexes with Cu(Ⅱ), Co(Ⅱ), Ni(Ⅱ) and Zn(Ⅱ) have been prepared and characterized by elemental analysis, IR, UV and 1H NMR techniques. The ligand and the complexes particurally the Co(Ⅱ) complex have antibacterial activities against Escherichia cocli and Staphylococcus aureus.
文摘Four hydroxamic acid derivaties were prepared by reaction of hydroxylamine hydrochloride with dimethylphthalate, dimethylisophthalate, dimethylterephthalate and dimethylsebacate respectively and characterized by IR and elemental analysis. The antibacterial activities to Escherichia coli and Staphylococcus aureus of phthaloyl, isophthaloyl, terephthaloyl and sebacoyl hydroxamic acids have been determined using paper disc method. The result indicates that their antibacterial activities to Escherichia coli are better than that to Staphylococcus aureus and among them the sebacoyl hydroxamic acid is the best one. No linear correlation was observed between the antibacterial activities and the concentration of the compounds, each has its optimum antibacterial concentration.
文摘The crystal structure and molecular structures of the title compound were determined using Xray analysis.The crystal belongs to monoclinic system with the space group P21/c,C21H20N4O2,with Mr=35839,a=12845(3),b=19334(4),c=073112(5)nm,β=9443(3)°,V=18103(4)nm3,Z=4,DC=132Mg·m-3,μ=0088mm-1,and F(000)=752.The final discrepancy factor R1=01508,and S=0942.The result showed that the dihedral angles between the two pyrazolinone rings and phenyl rings were 1267 and 798°,which indicated that these two planes roughly coplanar to each other forming a big conjugate system.
