Objective To observe value of 0D-1D coupling model and 3D fluid-structure interaction(FSI)model based on coronary CT angiography(CCTA)for displaying hemodynamic characteristics of coronary artery stenosis.Methods Base...Objective To observe value of 0D-1D coupling model and 3D fluid-structure interaction(FSI)model based on coronary CT angiography(CCTA)for displaying hemodynamic characteristics of coronary artery stenosis.Methods Based on CCTA data of the stenosed left anterior descending branch(LAD)in a patient with coronary heart disease,an 0D-1D coupling model and 3D FSI model were built,respectively.Then hemodynamic characteristic indexes,including the pressure,flow velocity and wall shear stress(WSS)were obtained in every 0.01 s during 1 s at 5 sampling points(i.e.sampling point 1—5)using these 2 models,respectively,and the consistencies of the results between models were evaluated with Spearman correlation coefficient r s.Results The time consuming for construction of 0D-1D coupling model and 3D FSI model was 0.033 min and 704 min,respectively.Both models showed basically distribution of the pressure,flow velocity and WSS of the stenosed LAD.For more details,the pressure at the stenosed segment of LAD and the proximal segment of stenosis were both higher,which gradually decreased at the distal segment of stenosis,and the flow velocity at the proximal segment of stenosis was in a relatively slow and uniform condition,with significantly increased flow velocity and WSS at the stenosed segment.Compared with 3D FSI model,0D-1D vascular coupling model was relatively unrefined and lack of distal flow lines when displaying blood flow velocity.For sampling point 2 at the stenosed segment of LAD,no significant consistency for pressure between 2 models was found(P=0.118),but strong consistency for the flow velocity and WSS(r s=0.730,0.807,both P<0.05).The consistencies of pressure,flow velocity and WSS between 2 models at the proximal and distal segment of stenosis,i.e.1,3—5 sampling points were week to moderate(r s=0.237—0.669,all P<0.05).Conclusion 0D-1D coupling model exhibited outstanding computational efficiency and might provide relatively reasonable results,while 3D FSI model showed higher accuracy for details and streamline when simulating LAD stenosis.展开更多
目的了解居家慢性心力衰竭患者家庭照顾者的生存质量并探讨其影响因素。方法方便性抽样选取155例居家慢性心力衰竭患者的家庭照顾者,采用家庭照顾者生存质量量表和一般自我效能感量表对其进行调查。结果居家慢性心力衰竭患者家庭照顾者...目的了解居家慢性心力衰竭患者家庭照顾者的生存质量并探讨其影响因素。方法方便性抽样选取155例居家慢性心力衰竭患者的家庭照顾者,采用家庭照顾者生存质量量表和一般自我效能感量表对其进行调查。结果居家慢性心力衰竭患者家庭照顾者的生存质量总分为(54.91±10.45)分;多元线性逐步回归分析显示,照顾者的自我效能、患者的纽约心脏病协会(the New York Heart Association,NYHA)心功能分级、照顾者的文化程度是居家慢性心力衰竭患者家庭照顾者生存质量的主要影响因素。结论居家慢性心力衰竭患者家庭照顾者的生存质量因照护任务而受损,尤其对于自我效能差、文化水平低、所照顾患者心功能差的照顾者更应给予关注。展开更多
文摘Objective To observe value of 0D-1D coupling model and 3D fluid-structure interaction(FSI)model based on coronary CT angiography(CCTA)for displaying hemodynamic characteristics of coronary artery stenosis.Methods Based on CCTA data of the stenosed left anterior descending branch(LAD)in a patient with coronary heart disease,an 0D-1D coupling model and 3D FSI model were built,respectively.Then hemodynamic characteristic indexes,including the pressure,flow velocity and wall shear stress(WSS)were obtained in every 0.01 s during 1 s at 5 sampling points(i.e.sampling point 1—5)using these 2 models,respectively,and the consistencies of the results between models were evaluated with Spearman correlation coefficient r s.Results The time consuming for construction of 0D-1D coupling model and 3D FSI model was 0.033 min and 704 min,respectively.Both models showed basically distribution of the pressure,flow velocity and WSS of the stenosed LAD.For more details,the pressure at the stenosed segment of LAD and the proximal segment of stenosis were both higher,which gradually decreased at the distal segment of stenosis,and the flow velocity at the proximal segment of stenosis was in a relatively slow and uniform condition,with significantly increased flow velocity and WSS at the stenosed segment.Compared with 3D FSI model,0D-1D vascular coupling model was relatively unrefined and lack of distal flow lines when displaying blood flow velocity.For sampling point 2 at the stenosed segment of LAD,no significant consistency for pressure between 2 models was found(P=0.118),but strong consistency for the flow velocity and WSS(r s=0.730,0.807,both P<0.05).The consistencies of pressure,flow velocity and WSS between 2 models at the proximal and distal segment of stenosis,i.e.1,3—5 sampling points were week to moderate(r s=0.237—0.669,all P<0.05).Conclusion 0D-1D coupling model exhibited outstanding computational efficiency and might provide relatively reasonable results,while 3D FSI model showed higher accuracy for details and streamline when simulating LAD stenosis.
文摘目的了解居家慢性心力衰竭患者家庭照顾者的生存质量并探讨其影响因素。方法方便性抽样选取155例居家慢性心力衰竭患者的家庭照顾者,采用家庭照顾者生存质量量表和一般自我效能感量表对其进行调查。结果居家慢性心力衰竭患者家庭照顾者的生存质量总分为(54.91±10.45)分;多元线性逐步回归分析显示,照顾者的自我效能、患者的纽约心脏病协会(the New York Heart Association,NYHA)心功能分级、照顾者的文化程度是居家慢性心力衰竭患者家庭照顾者生存质量的主要影响因素。结论居家慢性心力衰竭患者家庭照顾者的生存质量因照护任务而受损,尤其对于自我效能差、文化水平低、所照顾患者心功能差的照顾者更应给予关注。
