肥胖已成为严重危害人类健康的社会问题。现有大约十亿的成年人是超重,体重指数（body mass index,BMI）超过25,并且有3亿成年人是肥胖,BMI超过30。肥胖会导致严重的健康问题,降低生活期盼,对生活质量造成重要影响。肥胖和超体重会导致...肥胖已成为严重危害人类健康的社会问题。现有大约十亿的成年人是超重,体重指数（body mass index,BMI）超过25,并且有3亿成年人是肥胖,BMI超过30。肥胖会导致严重的健康问题,降低生活期盼,对生活质量造成重要影响。肥胖和超体重会导致高血压、2型糖尿病、冠状动脉心脏病等严重疾病，展开更多
The serine protease HtrA2/Omi is released from the mitochondrial intermembrane space following apoptotic stimuli.Once in the cytosol,HtrA2/Omi has been implicated in promoting cell death in caspase-dependent or caspas...The serine protease HtrA2/Omi is released from the mitochondrial intermembrane space following apoptotic stimuli.Once in the cytosol,HtrA2/Omi has been implicated in promoting cell death in caspase-dependent or caspase-independent pathway.On the other hand,HtrA2/Omi can refold and degrade misfolded proteins in the mitochondria during cell stress.展开更多
文摘The serine protease HtrA2/Omi is released from the mitochondrial intermembrane space following apoptotic stimuli.Once in the cytosol,HtrA2/Omi has been implicated in promoting cell death in caspase-dependent or caspase-independent pathway.On the other hand,HtrA2/Omi can refold and degrade misfolded proteins in the mitochondria during cell stress.
