Two novel complexes [Cu（TATP）（L-Leu）（H2O）]NO3·H2O and [Cu（TATP）L-Met)（H2O）]NO3·0.5H2O（TATP=1,4,8,9-tetraazatriphenylene,L-Leu=L-Leucinate,L-Met=L-Methioninate）were synthesized and characterized b...Two novel complexes [Cu（TATP）（L-Leu）（H2O）]NO3·H2O and [Cu（TATP）L-Met)（H2O）]NO3·0.5H2O（TATP=1,4,8,9-tetraazatriphenylene,L-Leu=L-Leucinate,L-Met=L-Methioninate）were synthesized and characterized by elemental analysis,molar conductivity,infrared absorption spectrum,electronic absorption spectrum and DTA-TGA.The results showed that both of the complexes had a distorted square-pyramidal geometry with two nitrogen atoms of TATP and one amino nitrogen and one carboxylate oxygen atoms of L-Leu/L-Met at the equatorial positions,and one water oxygen at the axial position.The SOD-Like activity of the complexes was determined by NBT-illumination method.The result indicated that the complexes possessed excellent SOD-like activity and showed 50% inhibition ration in the concentration of 0.355 μmol·L-1 and 0.185 μmol·L-1,respectively.The greater SOD-like activity of the complex[Cu（TATP）（L-Leu）（H2O）]NO3·H2O may be attributed to the smaller spatial hindrance of the side-chain group of L-Met.展开更多
Twelve[1,2,4]-triazolo[1,5-a]pyrimidine derivatives had been designed and synthesized by using substituted hydrazine hydrate as starting materials.The synthesized compounds were confirmed by elemental analysis,Infrare...Twelve[1,2,4]-triazolo[1,5-a]pyrimidine derivatives had been designed and synthesized by using substituted hydrazine hydrate as starting materials.The synthesized compounds were confirmed by elemental analysis,Infrared spectra and 1H NMR techniques.Preliminary bioassay indicated that some of them displayed good herbicidal activities.展开更多
Four new complexes: [Cu(NFA)(H2O)(8-HQ)] ClO4·H2O,[Cu(NFA)(Bipy)(H2O)]2ClO4·2.5H2O,[Cu(NFA)(Dafo)2(ClO4)] ClO4·7.5H2O and [Cu(NFA)(5,6-Dione)2 ] 2ClO4·9.5H2O(NFA= Norfloxacin,8-HQ=8 –hydroxyquinol...Four new complexes: [Cu(NFA)(H2O)(8-HQ)] ClO4·H2O,[Cu(NFA)(Bipy)(H2O)]2ClO4·2.5H2O,[Cu(NFA)(Dafo)2(ClO4)] ClO4·7.5H2O and [Cu(NFA)(5,6-Dione)2 ] 2ClO4·9.5H2O(NFA= Norfloxacin,8-HQ=8 –hydroxyquinoline,Bipy =2,2’-bipyridyl,Dafo =4,5-diazofluorene-9-ketone,and 5,6-Dione = 1,10-phenanthroline-5,6-dione),are synthesized and characterized by elemental analysis,molar conductivity,IR and Uv-vis spectroscopes.The interaction between the complexes and CT-DNA has been studied by fluorescence and UV spectra.The complexes are assayed against gram-positive and gram-negative bacteria by punch method.The results indicate that the complexes can interact with DNA by partial intercalation,and have strong antibacterial activities.展开更多
文摘Two novel complexes [Cu（TATP）（L-Leu）（H2O）]NO3·H2O and [Cu（TATP）L-Met)（H2O）]NO3·0.5H2O（TATP=1,4,8,9-tetraazatriphenylene,L-Leu=L-Leucinate,L-Met=L-Methioninate）were synthesized and characterized by elemental analysis,molar conductivity,infrared absorption spectrum,electronic absorption spectrum and DTA-TGA.The results showed that both of the complexes had a distorted square-pyramidal geometry with two nitrogen atoms of TATP and one amino nitrogen and one carboxylate oxygen atoms of L-Leu/L-Met at the equatorial positions,and one water oxygen at the axial position.The SOD-Like activity of the complexes was determined by NBT-illumination method.The result indicated that the complexes possessed excellent SOD-like activity and showed 50% inhibition ration in the concentration of 0.355 μmol·L-1 and 0.185 μmol·L-1,respectively.The greater SOD-like activity of the complex[Cu（TATP）（L-Leu）（H2O）]NO3·H2O may be attributed to the smaller spatial hindrance of the side-chain group of L-Met.
文摘Twelve[1,2,4]-triazolo[1,5-a]pyrimidine derivatives had been designed and synthesized by using substituted hydrazine hydrate as starting materials.The synthesized compounds were confirmed by elemental analysis,Infrared spectra and 1H NMR techniques.Preliminary bioassay indicated that some of them displayed good herbicidal activities.
文摘Four new complexes: [Cu(NFA)(H2O)(8-HQ)] ClO4·H2O,[Cu(NFA)(Bipy)(H2O)]2ClO4·2.5H2O,[Cu(NFA)(Dafo)2(ClO4)] ClO4·7.5H2O and [Cu(NFA)(5,6-Dione)2 ] 2ClO4·9.5H2O(NFA= Norfloxacin,8-HQ=8 –hydroxyquinoline,Bipy =2,2’-bipyridyl,Dafo =4,5-diazofluorene-9-ketone,and 5,6-Dione = 1,10-phenanthroline-5,6-dione),are synthesized and characterized by elemental analysis,molar conductivity,IR and Uv-vis spectroscopes.The interaction between the complexes and CT-DNA has been studied by fluorescence and UV spectra.The complexes are assayed against gram-positive and gram-negative bacteria by punch method.The results indicate that the complexes can interact with DNA by partial intercalation,and have strong antibacterial activities.
